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Background <p>Ventilator-associated pneumonia (VAP) is a significant complication in mechanically ventilated patients, increasing morbidity and mortality. Maintaining optimal endotracheal tube cuff pressure is crucial for prevention.</p> Objective <p>To evaluate the impact of 4-h versus 8-h endotracheal tube cuff pressure monitoring on VAP incidence in neuro-critically ill patients.</p> Methods <p>Eighty neuro-critically ill patients in the intensive care units of Alexandria university hospitals who received endotracheal intubation and underwent mechanical ventilation for more than 48&#xa0;h were divided into two equal groups of 40 cases. Endotracheal tube cuff pressure was monitored in the observation group at 8-h intervals, and in the study group every 4&#xa0;h, and adjusted to 30 cmH2O. Incidence of ventilator-associated pneumonia (VAP) was compared between the two groups for 7&#xa0;days.</p> Results <p>By day 7, VAP incidence was 40% (16/40) in the observation group and 25% (10/40) in the study group (p &gt; 0.05). No significant difference was found between groups regarding the proportion of time with acceptable cuff pressure.</p> Conclusion <p>In neuro-critically ill patients, 8-h endotracheal tube cuff pressure monitoring appears feasible for VAP management without a statistically significant increase in incidence compared to 4-h monitoring.</p>

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Monitoring of endotracheal tube cuff pressure in occurrence of ventilator associated pneumonia in neuro-critically ill patients

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月18日

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  • Dina Zidan,
  • Eslam Mahmoud Ali Ali Oweida,
  • Tayseer Mahmoud Zaitoun,
  • Emad Hamdy Hamouda Mohammed

摘要

Background

Ventilator-associated pneumonia (VAP) is a significant complication in mechanically ventilated patients, increasing morbidity and mortality. Maintaining optimal endotracheal tube cuff pressure is crucial for prevention.

Objective

To evaluate the impact of 4-h versus 8-h endotracheal tube cuff pressure monitoring on VAP incidence in neuro-critically ill patients.

Methods

Eighty neuro-critically ill patients in the intensive care units of Alexandria university hospitals who received endotracheal intubation and underwent mechanical ventilation for more than 48 h were divided into two equal groups of 40 cases. Endotracheal tube cuff pressure was monitored in the observation group at 8-h intervals, and in the study group every 4 h, and adjusted to 30 cmH2O. Incidence of ventilator-associated pneumonia (VAP) was compared between the two groups for 7 days.

Results

By day 7, VAP incidence was 40% (16/40) in the observation group and 25% (10/40) in the study group (p > 0.05). No significant difference was found between groups regarding the proportion of time with acceptable cuff pressure.

Conclusion

In neuro-critically ill patients, 8-h endotracheal tube cuff pressure monitoring appears feasible for VAP management without a statistically significant increase in incidence compared to 4-h monitoring.