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Background <p>Hospital-acquired pneumonia (HAP) is a major cause of morbidity and mortality in intensive care units (ICUs). This study aimed to determine the prevalence, risk factors, and outcomes of HAP in critically ill patients.</p> Methods <p>A retrospective analysis was conducted on 160 ICU patients. Clinical data, microbiological profiles, and outcomes were analyzed. Statistical associations were assessed using chi-square test and Fisher’s exact test.</p> Results <p>HAP prevalence was 52.5% (84/160), significantly higher than previous reports (<i>p</i> &lt; 0.05). The most common pathogens were <i>Acinetobacter baumannii</i> (57.1%), <i>Klebsiella pneumoniae</i> (23.8%), and <i>Pseudomonas aeruginosa</i> (7.1%). Risk factors included chronic hypertension (<i>p</i> &lt; 0.05), chronic kidney disease (<i>p</i> &lt; 0.05), and mechanical ventilation (94% of cases, <i>p</i> &lt; 0.05). HAP was associated with prolonged ICU stays (17.7&#xa0;days) and increased mortality (72.6%, <i>p</i> &lt; <i>0.05</i>).</p> Conclusion <p>HAP remains a significant burden in ICUs, with high prevalence, severe outcomes, and strong associations with mechanical ventilation and comorbidities.</p>

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Hospital-acquired pneumonia in patients hospitalized in the Intensive Care Unit of a National Hospital of Paraguay

  • 期刊论文

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  • 发表日期：

    2025年4月17日

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  • Karen Melgarejo Marecos,
  • Leticia Escobar Rivela,
  • Guillermo Insfran Méndez

摘要

Background

Hospital-acquired pneumonia (HAP) is a major cause of morbidity and mortality in intensive care units (ICUs). This study aimed to determine the prevalence, risk factors, and outcomes of HAP in critically ill patients.

Methods

A retrospective analysis was conducted on 160 ICU patients. Clinical data, microbiological profiles, and outcomes were analyzed. Statistical associations were assessed using chi-square test and Fisher’s exact test.

Results

HAP prevalence was 52.5% (84/160), significantly higher than previous reports (p < 0.05). The most common pathogens were Acinetobacter baumannii (57.1%), Klebsiella pneumoniae (23.8%), and Pseudomonas aeruginosa (7.1%). Risk factors included chronic hypertension (p < 0.05), chronic kidney disease (p < 0.05), and mechanical ventilation (94% of cases, p < 0.05). HAP was associated with prolonged ICU stays (17.7 days) and increased mortality (72.6%, p < 0.05).

Conclusion

HAP remains a significant burden in ICUs, with high prevalence, severe outcomes, and strong associations with mechanical ventilation and comorbidities.