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<p>Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease marked by the accumulation of PAS-positive proteinaceous material within distal airspaces. Diagnostic procedures include bronchoalveolar lavage, transbronchial lung biopsy (TBLB), and surgical lung biopsy (SLB). Recently, transbronchial lung cryobiopsy (TBLC) has emerged as a promising technique for diagnosing parenchymal lung diseases. This case series investigates the efficacy of TBLC in diagnosing PAP and compares it to traditional TBLB methods.</p>

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Role of transbronchial lung cryobiopsy in diagnosing pulmonary alveolar proteinosis—a five-case series

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年3月5日

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  • Vimal Raj Ramachandran,
  • Hsu-Yuan Chen,
  • Yu-Chu Kuo,
  • Wen-Chien Cheng,
  • Biing-Ru Wu,
  • Wei-Chih Liao,
  • Chia-Hung Chen,
  • Chih-Yen Tu

摘要

Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease marked by the accumulation of PAS-positive proteinaceous material within distal airspaces. Diagnostic procedures include bronchoalveolar lavage, transbronchial lung biopsy (TBLB), and surgical lung biopsy (SLB). Recently, transbronchial lung cryobiopsy (TBLC) has emerged as a promising technique for diagnosing parenchymal lung diseases. This case series investigates the efficacy of TBLC in diagnosing PAP and compares it to traditional TBLB methods.