Objective <p>This work is a feasibility study of using barbed sutures for managing obstructive sleep apnea (OSA) patients with mainly retropalatal collapse in our institution.</p> Study design <p>Retrospective cohort study.</p> Setting <p>Tertiary university hospital. </p> Methods <p>Twenty patients with OSA were enrolled. All cases were evaluated preoperatively using the Epworth Sleepiness Scale (ESS), polysomnography (PSG), and sleep endoscopy. Barbed Reposition Pharyngoplasty (BRP) was performed for all patients by a single surgeon. The technique was evaluated regarding operative time, postoperative symptom relief, and complications. Surgical success was defined as a reduction in the AHI by 50% and AHI &lt; 20 after surgery.</p> Results <p>The study included 15 males and five females, with a mean age of 45 ± 10 years. The mean operative time was 19.25 ± 3.73 min. The mean postoperative ESS was 7.75, significantly better than the pre-operative ESS: 12.3 (<i>P</i> = 0.001). The mean AHI post-operatively was significantly lower than the pre-operative measure (11.30 ± 6.31 compared to 30.05 ± 20.18 (<i>Z</i> = 3.921, <i>P</i> value &lt; 0.001)). The surgical success was estimated to be 70%. Postoperative partial suture extrusion occurred in 3 patients (15%) with no symptoms.</p> Conclusion <p>BRP is an easy, safe, and effective surgical technique for managing retropalatal collapse in patients with snoring and/or OSA.</p>