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Background <p>Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty.</p> Results <p>Demographic characters showed no statistical differences in age (<i>p</i> = 0.62) or gender (<i>p</i> = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (<i>p</i> &gt; 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (<i>p</i> = 0.03 and <i>p</i> = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (<i>p</i> = 1).</p> Conclusion <p>The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients.</p>

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Effect of platelet-rich fibrin on wound healing, adhesions, and hemostasis after inferior turbinoplasty surgery

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月3日

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  • Abdelhakim Fouad Ghallab,
  • Mohamed Fahmy Shendy,
  • Samer Badie Kamel,
  • Mohamed Ali Adam,
  • Mohamed Goda Elnems

摘要

Background

Inferior turbinate enlargement is a prevalent cause of chronic nasal obstruction, often requiring surgical intervention when medical treatment fails. Platelet-rich fibrin (PRF) has been reported to mitigate post-operative complications following nasal surgeries. This work aims to evaluate the efficacy of PRF on hemostasis, adhesions, crust formation, and mucosal healing post-turbinoplasty.

Results

Demographic characters showed no statistical differences in age (p = 0.62) or gender (p = 0.342), but the mean operative time was significantly shorter in the non-PRF group (22.80 ± 2.02) compared to the PRF group (p > 0.001). Early hemostasis and prevention of crustation were significantly better in the PRF group (p = 0.03 and p = 0.024, respectively). No significant difference was observed regarding adhesions between the groups (p = 1).

Conclusion

The PRF membrane is an affordable and easy method that acts as a protective layer, reducing crusting, ensuring hemostasis, promoting healing by shortening the period of recovery post inferior turbinoplasty and so improving the quality of life of the patients.