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<p>Avian influenza A (H5N1) virus infection can cause severe pneumonia, but the development of acute respiratory distress syndrome (ARDS) and hemophagocytic lymphohistiocytosis (HLH) syndrome is rare. We report a case of rapidly progressive and fatal H5N1 infection that was complicated by HLH and multiorgan failure. The purpose is to highlight the potential for H5N1 infection to trigger life-threatening complications, including ARDS and HLH syndrome. Early recognition and aggressive treatment may improve survival in these critically ill patients.</p>

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ARDS and HLH syndromes induced by avian flu pneumonia in a farm worker patient

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月5日

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  • Hamdy Ibrahim,
  • Mohamed Saleh,
  • Mohamed EL Sawy,
  • Ahmed EL sisi,
  • Ahmed Samir EL bahwashy,
  • Abdel Rahman Eliwa,
  • Youssef Eshak Naguib

摘要

Avian influenza A (H5N1) virus infection can cause severe pneumonia, but the development of acute respiratory distress syndrome (ARDS) and hemophagocytic lymphohistiocytosis (HLH) syndrome is rare. We report a case of rapidly progressive and fatal H5N1 infection that was complicated by HLH and multiorgan failure. The purpose is to highlight the potential for H5N1 infection to trigger life-threatening complications, including ARDS and HLH syndrome. Early recognition and aggressive treatment may improve survival in these critically ill patients.