Ventilatory functions in response to bicycle ergometry training in boys with Duchenne muscular dystrophy

Background

Duchenne muscular dystrophy (DMD) is the popular kind of muscular dystrophy in childhood characterized by gradual motor decline and respiratory failure which ultimately results in death.

Purpose

This research sought to determine the impact of bicycle ergometer on ventilatory functions and motor ability in boys with DMD.

Design

Single-blind, randomized controlled experiment.

Methods

Thirty boys with DMD were randomly split into two similar groups. A selected physical therapy regimen was implemented for the control and ergometer groups, while a bicycle ergometer was implemented only for the ergometer group. All boys were assessed for respiratory functions covering forced expiratory volume in the first second (FEV₁) and forced vital capacity (FVC) using spirometry, and motor ability using the North Star Ambulatory Assessment (NSAA). The rehabilitation session was conducted three times a week for 12 successive weeks.

Results

Post-rehabilitation findings in the two groups detected a notable rise in every evaluated variable. However, the ergometer group revealed a notable rise in all assessed variables in relation to that of the control group.

Conclusion

Bicycle ergometer as an aerobic exercise could promote ventilatory functions and motor ability in boys with DMD.

Trial registration

Clinicaltrials.gov (No. NCT05849688).