Cholestatic liver injury secondary to over-the-counter cyproheptadine: case report and review of literature

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2024年4月24日

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Ayush Agarwal,
Arpit Shastri,
C. P. Ganesh,
Malvika Shastri,
Suvradeep Mitra,
Debadrita Ray,
Arka De

摘要

Background

Cyproheptadine is an easily available over-the-counter first-generation antihistaminic that is often used as an appetite stimulant. Although it is usually a safe drug, rare instances of drug-induced liver injury may occur.

Case presentation

We report a case of cholestatic liver injury secondary to cyproheptadine in a young pharmacy student with chronic hepatitis B and review the literature of cyproheptadine-induced liver injury.

Conclusion

Although cyproheptadine is largely a safe drug, its potential for significant liver toxicity cannot be ignored.