Scholarlink

Purpose <p>To standardize the interpretation of adnexal lesions, several magnetic resonance imaging (MRI)-based scoring systems have been developed, including the Ovarian-Adnexal Reporting and Data System (O-RADS), the ADNEX-MR score, and the modified ADNEX-MR score. The aim of this study was to compare the diagnostic performance of the standard ADNEX-MR score, the O-RADS MRI system, and the modified ADNEX-MR score in the characterization of adnexal masses, using histopathological diagnosis as the reference standard.</p> Materials and methods <p>A prospective cross-sectional study included 70 females with 88 adnexal masses. All patients underwent conventional pelvic MRI with diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE). Each lesion was classified according to the O-RADS MRI system and both classical and modified ADNEX-MR scoring systems.</p> Results <p>The standard ADNEX-MR score demonstrated excellent diagnostic performance, with high sensitivity (91.2%) and specificity (97.1%). The O-RADS MRI system showed comparable results, with similar sensitivity (91%) and slightly lower specificity (94%). The modified ADNEX-MR score, which incorporates diffusion-weighted imaging as an essential parameter, achieved higher sensitivity (95%) and lower specificity (80%).</p> Conclusion <p>The ADNEX-MR and O-RADS MRI systems demonstrated high and balanced diagnostic performance for adnexal lesion characterization. The modified ADNEX-MR score improved sensitivity and negative predictive value, enhancing malignancy detection, particularly in indeterminate cases or when DCE MRI is unavailable, albeit at the expense of reduced specificity.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

MRI-based risk stratification of adnexal lesions: comparative diagnostic performance of O-RADS, ADNEX-MR and modified ADNEX-MR scoring systems

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月29日

查看全文
  • Carmen Ali Zarad,
  • Asmaa Yussif,
  • Khaled Abd El-Baky,
  • Mohamed Elrakhawy,
  • Shaimaa Yussif,
  • Waleed Abo Shanab

摘要

Purpose

To standardize the interpretation of adnexal lesions, several magnetic resonance imaging (MRI)-based scoring systems have been developed, including the Ovarian-Adnexal Reporting and Data System (O-RADS), the ADNEX-MR score, and the modified ADNEX-MR score. The aim of this study was to compare the diagnostic performance of the standard ADNEX-MR score, the O-RADS MRI system, and the modified ADNEX-MR score in the characterization of adnexal masses, using histopathological diagnosis as the reference standard.

Materials and methods

A prospective cross-sectional study included 70 females with 88 adnexal masses. All patients underwent conventional pelvic MRI with diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE). Each lesion was classified according to the O-RADS MRI system and both classical and modified ADNEX-MR scoring systems.

Results

The standard ADNEX-MR score demonstrated excellent diagnostic performance, with high sensitivity (91.2%) and specificity (97.1%). The O-RADS MRI system showed comparable results, with similar sensitivity (91%) and slightly lower specificity (94%). The modified ADNEX-MR score, which incorporates diffusion-weighted imaging as an essential parameter, achieved higher sensitivity (95%) and lower specificity (80%).

Conclusion

The ADNEX-MR and O-RADS MRI systems demonstrated high and balanced diagnostic performance for adnexal lesion characterization. The modified ADNEX-MR score improved sensitivity and negative predictive value, enhancing malignancy detection, particularly in indeterminate cases or when DCE MRI is unavailable, albeit at the expense of reduced specificity.