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Background <p>Expanding the use of Magnetic Resonance Imaging (MRI) for breast cancer detection offers clear diagnostic advantages (highest sensitivity &gt; 90%); however, dynamic contrast-enhanced MRI (DCE-MRI) is lengthy. More accessible faster alternatives, such as abbreviated MRI (AB-MRI) protocols, have been developed to maintain the high diagnostic power of conventional DCE-MRI while significantly reducing both scan and interpretation times. The aim of this study was to evaluate the diagnostic efficacy, clinical utility, and radiological characteristics of AB-MRI protocols in comparison with conventional DCE-MRI.</p> Results <p>This prospective cross-sectional analytical study comprised 93 female patients, with 186 breasts assessed and a total of 206 individual findings identified. A full DCE-MRI protocol was acquired, from which two abbreviated protocols (Focused Abbreviated Sequence Technique (FAST) and Abridged) were derived. Perfect agreement was observed between the dynamic and abridged protocols across lesion Breast Imaging-Reporting and Data System (BI-RADS) classification (<i>κ</i> = 1.000, <i>p</i> &lt; 0.001). The FAST protocol showed slightly lower but still excellent agreement in BI-RADS classification (<i>κ</i> = 0.879). Diagnostic performance analysis revealed that the dynamic and abridged protocols had similar indices, with sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy of 95.4%, 97.2%, 93.9%, 97.1%, and 96.6% respectively, for breast cancer detection. The FAST protocol yielded comparable results, with sensitivity of 95.4%, specificity of 95.7%, PPV of 91.2%, NPV of 97.8%, and overall accuracy of 95.6%.</p> Conclusions <p>The abridged breast MRI protocol is a reliable substitute for full DCE-MRI, thus it can be used in breast cancer screening and in patients with poor prolonged prone positioning tolerance. Although the FAST protocol is more time-efficient, the exclusion of T2 and diffusion-weighted imaging may influence lesion detection and characterization, particularly for benign, inflammatory, and deep lesions. While no missed cancers were encountered in this study, the limited number of malignant cases mandates cautious interpretation, and further large-scale, multicenter studies are warranted to validate these results and guide protocol selection.</p>

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Utility of abbreviated breast Magnetic Resonance Imaging for the detection and characterization of breast lesions: comparison with full-protocol dynamic breast Magnetic Resonance Imaging

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月18日

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  • Lamiaa Mohamed Bassam Hashem,
  • Yasmin Essameldin Abdalla Khalifa,
  • Alyaa Farouk Radwan Torad,
  • Yasmine Ahmed Elsayed Sawy,
  • Mahmoud Abdelmonem Ameen,
  • Ghada Ali Sheta

摘要

Background

Expanding the use of Magnetic Resonance Imaging (MRI) for breast cancer detection offers clear diagnostic advantages (highest sensitivity > 90%); however, dynamic contrast-enhanced MRI (DCE-MRI) is lengthy. More accessible faster alternatives, such as abbreviated MRI (AB-MRI) protocols, have been developed to maintain the high diagnostic power of conventional DCE-MRI while significantly reducing both scan and interpretation times. The aim of this study was to evaluate the diagnostic efficacy, clinical utility, and radiological characteristics of AB-MRI protocols in comparison with conventional DCE-MRI.

Results

This prospective cross-sectional analytical study comprised 93 female patients, with 186 breasts assessed and a total of 206 individual findings identified. A full DCE-MRI protocol was acquired, from which two abbreviated protocols (Focused Abbreviated Sequence Technique (FAST) and Abridged) were derived. Perfect agreement was observed between the dynamic and abridged protocols across lesion Breast Imaging-Reporting and Data System (BI-RADS) classification (κ = 1.000, p < 0.001). The FAST protocol showed slightly lower but still excellent agreement in BI-RADS classification (κ = 0.879). Diagnostic performance analysis revealed that the dynamic and abridged protocols had similar indices, with sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy of 95.4%, 97.2%, 93.9%, 97.1%, and 96.6% respectively, for breast cancer detection. The FAST protocol yielded comparable results, with sensitivity of 95.4%, specificity of 95.7%, PPV of 91.2%, NPV of 97.8%, and overall accuracy of 95.6%.

Conclusions

The abridged breast MRI protocol is a reliable substitute for full DCE-MRI, thus it can be used in breast cancer screening and in patients with poor prolonged prone positioning tolerance. Although the FAST protocol is more time-efficient, the exclusion of T2 and diffusion-weighted imaging may influence lesion detection and characterization, particularly for benign, inflammatory, and deep lesions. While no missed cancers were encountered in this study, the limited number of malignant cases mandates cautious interpretation, and further large-scale, multicenter studies are warranted to validate these results and guide protocol selection.