Background <p>Medical imaging is the most common source of ionizing radiation exposure. Despite its evident benefits, ionizing radiation presents a variety of health risks. While the cancer risk cannot be totally eliminated, a risk–benefit analysis must be performed to avoid radiation dangers produced by ionizing radiation. The risk of cancer might be further decreased if professionals are aware of the problem and take precautions. Among the healthcare staff, those working on fluoroscopy and interventional cardiology are most exposed to ionizing radiation, primarily from scatter during procedures.</p> Methodology <p>The current study sought to examine radiology staff members' grasp of radiation hazards by reviewing the literature available on their awareness and evaluating information on radiation-induced cancer that may be related with radiation exposure during interventional fluoroscopy. The authors employed a variety of search engines to locate high-quality original research papers. Out of the 84 publications initially assessed, 28 research articles satisfied inclusion requirements, which were separated into two categories: those that addressed radiation-induced cancer awareness and those that supported radiation-related health consequences.</p> Result <p>According to the findings, imaging technologists and radiation professionals were not well-versed on radiation issues. Overall, only 37% of radiology workers understood radiation safety and cancer dangers. According to data analysis, 53.4% accurately assessed the danger, 39.8% underestimated or rejected cancer risk, and 3.6% were unaware of radiation risks. Furthermore, interventional staff who were exposed to ionizing radiation had greater occurrences of brain, thyroid, breast, and basal cell carcinomas. Interventional cardiologists were particularly susceptible to left-sided brain tumors. Even with the use of protective equipment, elevated cancer risks were still observed among interventional staff, which may reflect cumulative exposure or limitations in protective practices. Interventional staff with a lack of comprehension and awareness of the risks of occupational exposure to ionizing radiation had a greater prevalence of cancer.</p> Conclusion <p>Ionizing radiation provides significant health dangers to radiation workers that must be addressed. Radiology professionals must receive better radiation safety education. Radiation-induced health concerns in interventional radiology must be reduced through stricter protocols, improved use of protective equipment and awareness campaigns.</p>