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Background <p>Dementia results from various diseases and injuries affecting the brain, with Alzheimer’s disease being the most common form, contributing to 60–70% of cases. Diagnosing dementia and assessing the severity of cognitive symptoms often involve various evaluation tools. One commonly used tool is the Montreal Cognitive Assessment—Indonesian (MOCA-INA), which is specifically designed to evaluate cognitive function across multiple domains.</p> Methods <p>MRI results of 28 dementia patients who have undergone MOCA-INA scoring at RSUP Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, from January 2022 to December 2023, were selected. MRI parameters and MOCA-INA score were assessed using the Spearman correlation test. Correlation between variables was evaluated based on the correlation coefficient, which indicates the direction and strength of the correlation.</p> Results <p>In this study, no statistical differences were found between multiple MRI parameters and MOCA-INA scores. However, weak inverse relationships were noted for the GCA and MTA scale, and the remaining Kolam and Fazekas score was found to have a positive relationship with the MOCA-INA score.</p> Conclusion <p>Parameters such as clinical status, GCA scale, MTA scale, Fazekas scale, strategic infarction, Koedam score, stroke, hypertension, diabetes mellitus, dyslipidemia, and cardiovascular disease do not have significant correlations with MoCA-INA scores. This may be caused by a relatively small sample size and further study with a broader and larger sample size may help in overcoming the issue.</p>

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Correlation of magnetic resonance imaging parameters with montreal cognitive assessment-Indonesian (MOCA-INA) score in dementia patients at Prof. Dr. IGNG Ngoerah General Hospital, Denpasar, Bali, Indonesia

  • 期刊论文

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  • 发表日期：

    2025年3月5日

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  • Made Widhi Asih,
  • Elysanti Dwi Martadiani,
  • I Wayan Gede Artawan Eka Putra,
  • Felicia Nike,
  • Putri Ayu Ratnasari,
  • Nugra Arenz Raturandang,
  • Jessieca Liusen,
  • Anak Agung Parama Swari Khrisna,
  • Luh Dindi Ayu Surya Kanti,
  • Adsel Kartadinata

摘要

Background

Dementia results from various diseases and injuries affecting the brain, with Alzheimer’s disease being the most common form, contributing to 60–70% of cases. Diagnosing dementia and assessing the severity of cognitive symptoms often involve various evaluation tools. One commonly used tool is the Montreal Cognitive Assessment—Indonesian (MOCA-INA), which is specifically designed to evaluate cognitive function across multiple domains.

Methods

MRI results of 28 dementia patients who have undergone MOCA-INA scoring at RSUP Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, from January 2022 to December 2023, were selected. MRI parameters and MOCA-INA score were assessed using the Spearman correlation test. Correlation between variables was evaluated based on the correlation coefficient, which indicates the direction and strength of the correlation.

Results

In this study, no statistical differences were found between multiple MRI parameters and MOCA-INA scores. However, weak inverse relationships were noted for the GCA and MTA scale, and the remaining Kolam and Fazekas score was found to have a positive relationship with the MOCA-INA score.

Conclusion

Parameters such as clinical status, GCA scale, MTA scale, Fazekas scale, strategic infarction, Koedam score, stroke, hypertension, diabetes mellitus, dyslipidemia, and cardiovascular disease do not have significant correlations with MoCA-INA scores. This may be caused by a relatively small sample size and further study with a broader and larger sample size may help in overcoming the issue.