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Purpose <p>The aim of this study was to compare total perioperative blood loss in patients undergoing total knee arthroplasty (TKA) in different ABO blood types.</p> Methods <p>This study was approved by the Institutional Review Board of our hospital (IRB No. 1510) on 2 February 2015. A total of 260 knees undergoing unilateral primary cemented cruciate-retaining TKA for knee osteoarthritis were retrospectively registered. Perioperative total blood loss was calculated for each blood types based on the change in hematocrit from pre- to postoperative day 7, preoperative height and weight. Differences in blood loss among the four ABO blood types were assessed. The association between blood type (O versus others) and total blood loss was further evaluated after adjusting for baseline characteristics through inverse probability of treatment weighting (IPTW).</p> Results <p>The study population was divided based on the ABO blood type: type O, 87; type A, 82; type B, 54; and type AB, 37. The mean total blood loss was 829 ± 370&#xa0;ml for type O, 702 ± 384&#xa0;ml for type A, 574 ± 361&#xa0;ml for type B, and 528 ± 282&#xa0;ml for type AB. Patients with blood Type O had significantly higher blood loss than all other blood types. After IPTW adjustment, mean total blood loss remained higher in type O (790 ± 370&#xa0;ml) compared to other blood types (613 ± 364&#xa0;ml).</p> Conclusion <p>These findings suggest that blood type O may be associated with increased perioperative blood loss in TKA.</p>

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Blood type O increased perioperative blood loss in total knee arthroplasty: a propensity score-based inverse probability of treatment weighting matched analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月25日

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  • Yoshihito Suda,
  • Naoki Nakano,
  • Yoshinori Takashima,
  • Masanori Tsubosaka,
  • Tomoyuki Kamenaga,
  • Yuichi Kuroda,
  • Kazunari Ishida,
  • Shinya Hayashi,
  • Ryosuke Kuroda,
  • Tomoyuki Matsumoto

摘要

Purpose

The aim of this study was to compare total perioperative blood loss in patients undergoing total knee arthroplasty (TKA) in different ABO blood types.

Methods

This study was approved by the Institutional Review Board of our hospital (IRB No. 1510) on 2 February 2015. A total of 260 knees undergoing unilateral primary cemented cruciate-retaining TKA for knee osteoarthritis were retrospectively registered. Perioperative total blood loss was calculated for each blood types based on the change in hematocrit from pre- to postoperative day 7, preoperative height and weight. Differences in blood loss among the four ABO blood types were assessed. The association between blood type (O versus others) and total blood loss was further evaluated after adjusting for baseline characteristics through inverse probability of treatment weighting (IPTW).

Results

The study population was divided based on the ABO blood type: type O, 87; type A, 82; type B, 54; and type AB, 37. The mean total blood loss was 829 ± 370 ml for type O, 702 ± 384 ml for type A, 574 ± 361 ml for type B, and 528 ± 282 ml for type AB. Patients with blood Type O had significantly higher blood loss than all other blood types. After IPTW adjustment, mean total blood loss remained higher in type O (790 ± 370 ml) compared to other blood types (613 ± 364 ml).

Conclusion

These findings suggest that blood type O may be associated with increased perioperative blood loss in TKA.