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<p>Plants employ a two-tiered immune system to defend against pathogen invasion. While understanding immune activation mechanisms is crucial for designing disease-resistant crops, evolutionary divergence often imposes functional constraints on the deployment of immune receptors across distantly related species. Recent research by Du et al. (Cell, 2025,&#xa0;<a href="https://doi.org/10.1016/j.cell.2025.05.028">https://doi.org/10.1016/j.cell.2025.05.028</a>) has addressed this issue, overcoming restricted taxonomic functionality and enabling the broader utilization of nucleotide-binding leucine-rich repeat receptors (NLRs).</p>

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Engineering plant immunity: from nucleotide-binding leucine-rich repeat receptor functional mechanisms to practical applications

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月26日

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  • You-Liang Peng

摘要

Plants employ a two-tiered immune system to defend against pathogen invasion. While understanding immune activation mechanisms is crucial for designing disease-resistant crops, evolutionary divergence often imposes functional constraints on the deployment of immune receptors across distantly related species. Recent research by Du et al. (Cell, 2025, https://doi.org/10.1016/j.cell.2025.05.028) has addressed this issue, overcoming restricted taxonomic functionality and enabling the broader utilization of nucleotide-binding leucine-rich repeat receptors (NLRs).