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<p>Congenital round cell soft tissue sarcoma with metastasis to the placenta is rarely described. We report a case of a large soft tissue sarcoma of the left neck from a female fetus delivered at 36 weeks and 3 days with metastasis to the stem villous vessels of the placenta. The tumor showed mixed features of Ewing sarcoma/primitive neuroectodermal tumor (PNET) and infantile fibrosarcoma with ETV6 :: NTRK3 fusion gene transcript. The clinical significance and diagnostic pitfalls are discussed.</p>

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Congenital soft tissue sarcoma of the neck with placental metastasis: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年6月29日

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  • Michelle Nguyen,
  • Jennifer Ahn,
  • Art Mendoza,
  • Chris Wixom,
  • Omid Bakhtar,
  • Peilin Zhang

摘要

Congenital round cell soft tissue sarcoma with metastasis to the placenta is rarely described. We report a case of a large soft tissue sarcoma of the left neck from a female fetus delivered at 36 weeks and 3 days with metastasis to the stem villous vessels of the placenta. The tumor showed mixed features of Ewing sarcoma/primitive neuroectodermal tumor (PNET) and infantile fibrosarcoma with ETV6 :: NTRK3 fusion gene transcript. The clinical significance and diagnostic pitfalls are discussed.