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Background <p>Angiocentric glioma (AG) is a rare form of brain tumor first reported in 2005. It is mainly characterized by cortical epileptogenic lesions with an angiocentric arrangement of tumor cells. Cystic degeneration is an uncommon radiological manifestation of this disease.</p> Case description <p>We present the case of a 33-year-old woman who was treated with microsurgical resection. The objective of this report is to describe the clinical presentation, imaging and histopathological findings, treatment, and outcome, as well as to review the relevant literature on AG.</p> Conclusion <p>AG is a rare epileptogenic glioma, primarily affecting children and young adults. Histopathological examination remains the gold standard for diagnosis. Treatment consists of complete surgical resection, which typically resolves the clinical symptoms. Adjuvant radiotherapy may be considered depending on the tumor’s Ki-67 index.</p>

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Cystic angiocentric glioma: a rare form of brain tumor

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月6日

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  • Alejandra Arévalo-Sáenz,
  • Fernando José Rascón-Ramírez,
  • Gloria de Antonio Palomo,
  • Pedro Alonso-Lera

摘要

Background

Angiocentric glioma (AG) is a rare form of brain tumor first reported in 2005. It is mainly characterized by cortical epileptogenic lesions with an angiocentric arrangement of tumor cells. Cystic degeneration is an uncommon radiological manifestation of this disease.

Case description

We present the case of a 33-year-old woman who was treated with microsurgical resection. The objective of this report is to describe the clinical presentation, imaging and histopathological findings, treatment, and outcome, as well as to review the relevant literature on AG.

Conclusion

AG is a rare epileptogenic glioma, primarily affecting children and young adults. Histopathological examination remains the gold standard for diagnosis. Treatment consists of complete surgical resection, which typically resolves the clinical symptoms. Adjuvant radiotherapy may be considered depending on the tumor’s Ki-67 index.