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<p>Cranioplasty, a critical neurosurgical procedure following decompressive craniectomy in traumatic brain injury (TBI) patients, restores skull integrity and significantly enhances neurological recovery and cerebral hemodynamics. Recent findings by Liu et al. emphasize its role in improving cerebral blood flow, particularly in severe TBI cases, while highlighting the need for advanced imaging techniques like helmet-based ultrasound for improved postoperative monitoring. However, reliance on CT perfusion limits long-term vascular and cognitive assessments. Future research should incorporate functional MRI, diffusion tensor imaging, and perfusion MRI to better predict and monitor functional outcomes. Emerging technologies, including bioresorbable, neuro-regenerative, and sensor-embedded implants, are poised to transform cranioplasty from a passive reconstructive approach into an active therapeutic platform. These innovations enable real-time monitoring and may support angiogenesis and neural repair. Positioned at the intersection of neurosurgery, neurorehabilitation, and bioengineering, cranioplasty holds transformative potential for enhancing neuroplasticity and long-term recovery through interdisciplinary, research-driven advancements.</p>

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Cranioplasty and cerebral perfusion recovery in TBI: expanding the neurovascular narrative

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月29日

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  • Haider Imran,
  • Zahra Ali Haque,
  • Amal Khan

摘要

Cranioplasty, a critical neurosurgical procedure following decompressive craniectomy in traumatic brain injury (TBI) patients, restores skull integrity and significantly enhances neurological recovery and cerebral hemodynamics. Recent findings by Liu et al. emphasize its role in improving cerebral blood flow, particularly in severe TBI cases, while highlighting the need for advanced imaging techniques like helmet-based ultrasound for improved postoperative monitoring. However, reliance on CT perfusion limits long-term vascular and cognitive assessments. Future research should incorporate functional MRI, diffusion tensor imaging, and perfusion MRI to better predict and monitor functional outcomes. Emerging technologies, including bioresorbable, neuro-regenerative, and sensor-embedded implants, are poised to transform cranioplasty from a passive reconstructive approach into an active therapeutic platform. These innovations enable real-time monitoring and may support angiogenesis and neural repair. Positioned at the intersection of neurosurgery, neurorehabilitation, and bioengineering, cranioplasty holds transformative potential for enhancing neuroplasticity and long-term recovery through interdisciplinary, research-driven advancements.