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Background <p>Glioblastomas (GBMs) are the most common malignant primary brain tumours, accounting for a significant portion of brain tumour-related morbidity and mortality. However, it is more commonly seen in the male population and rarely occurs in paediatric cases. Also, when it occurs in paediatrics, the giant cell type has been shown to be the most common type amongst children. Our inex case is a female paediatric patient who was diagnosed with glioblastoma multiforme.</p> Case presentation <p>This was a case of a 14-year-old female teenager who presented on account of limping, inability to adduct the right digits to hold a pen and right-sided hemiparesis. First symptoms showed a week prior to presentation. Brain scan showed a left parietal mixed intensity space occupying lesion. A gross total tumour resection surgery was done and after 7&#xa0;h, all neurological deficits were gone. An analysis of the tumour was done in the pathology laboratory and showed a gliosarcomatous glioblastoma multiforme tumour, on histology. Following surgery, patient has been doing so well.</p> Conclusion <p>Glioblastoma is very rare in paediatric patients; however, when it presents, it presents with varying characteristics. It is more common in males, although women have a higher survival rate. This may be linked to behavioural, hormonal, or genetic reason. GTR as against STR in GBM gives clinically and prognostically better outcomes. Finally, timely and precision surgeries are most vital to a good outcome.</p>

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A rare case of a gliosarcoma tumour in a 14-year-old female teenager: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月17日

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  • Daniel David Otobo,
  • Joseph Obande,
  • Adekola Olomo,
  • Ega Otorkpa,
  • Christopher Okpanachi,
  • Ejieke Elekwa,
  • Stanley Orji,
  • Stanley Lemchi,
  • Geoffrey Ndu,
  • Yusuf Dawan

摘要

Background

Glioblastomas (GBMs) are the most common malignant primary brain tumours, accounting for a significant portion of brain tumour-related morbidity and mortality. However, it is more commonly seen in the male population and rarely occurs in paediatric cases. Also, when it occurs in paediatrics, the giant cell type has been shown to be the most common type amongst children. Our inex case is a female paediatric patient who was diagnosed with glioblastoma multiforme.

Case presentation

This was a case of a 14-year-old female teenager who presented on account of limping, inability to adduct the right digits to hold a pen and right-sided hemiparesis. First symptoms showed a week prior to presentation. Brain scan showed a left parietal mixed intensity space occupying lesion. A gross total tumour resection surgery was done and after 7 h, all neurological deficits were gone. An analysis of the tumour was done in the pathology laboratory and showed a gliosarcomatous glioblastoma multiforme tumour, on histology. Following surgery, patient has been doing so well.

Conclusion

Glioblastoma is very rare in paediatric patients; however, when it presents, it presents with varying characteristics. It is more common in males, although women have a higher survival rate. This may be linked to behavioural, hormonal, or genetic reason. GTR as against STR in GBM gives clinically and prognostically better outcomes. Finally, timely and precision surgeries are most vital to a good outcome.