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Background <p>Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm primarily observed in the pleura. Instances of intracranial solitary fibrous tumors are exceedingly rare. Achieving accurate preoperative diagnosis remains challenging. This report aims to enhance the understanding of this rare disease, shedding light on diagnostic intricacies, and therapeutic considerations.</p> Case presentation <p>Herein, we present a case involving an enormous SFT situated at the anterior skull base, initially misdiagnosed as meningioma. Comprehensive scrutiny of preoperative images, intraoperative observations, pathological analyses, and subsequent treatment strategies is detailed.</p> Conclusion <p>Intracranial SFT, frequently misdiagnosed radiologically as meningiomas, may originate in the subarachnoid region, emphasizing the necessity of surgical resection and the potential benefit of postoperative radiotherapy to enhance treatment efficacy.</p>

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A preoperative misdiagnosis case: report of an enormous solitary fibrous tumor at the anterior skull base

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月31日

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  • Shiqi Kong,
  • Jingliang You,
  • Yapeng Wang,
  • Jingbo Yan,
  • Sajjad Muhammad,
  • Rui Zhang

摘要

Background

Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm primarily observed in the pleura. Instances of intracranial solitary fibrous tumors are exceedingly rare. Achieving accurate preoperative diagnosis remains challenging. This report aims to enhance the understanding of this rare disease, shedding light on diagnostic intricacies, and therapeutic considerations.

Case presentation

Herein, we present a case involving an enormous SFT situated at the anterior skull base, initially misdiagnosed as meningioma. Comprehensive scrutiny of preoperative images, intraoperative observations, pathological analyses, and subsequent treatment strategies is detailed.

Conclusion

Intracranial SFT, frequently misdiagnosed radiologically as meningiomas, may originate in the subarachnoid region, emphasizing the necessity of surgical resection and the potential benefit of postoperative radiotherapy to enhance treatment efficacy.