Scholarlink

Background <p>Corpus callosum infarctions are rare due to the region’s dual vascular supply and often present with nonspecific or atypical symptoms. The resulting diagnostic delay may impact management and outcomes.</p> Case presentation <p>We report a case of a female patient in her early sixties with a background of hypertension, diabetes mellitus, and stage IV chronic kidney disease. She presented with acute coronary syndrome and pulmonary edema. During hospitalization, she developed a new-onset cognitive decline, with a Mini-Mental State Examination (MMSE) score of 16/30. Neurological examination revealed no focal deficits but marked cognitive slowing. MRI of the brain showed acute infarction involving the entire corpus callosum. Workup for embolic sources and alternative diagnoses was unremarkable. The patient was managed conservatively due to comorbidities and gradually improved. Her MMSE improved to 24/30 at 1-week follow-up.</p> Conclusion <p>This case highlights the importance of considering corpus callosum infarction in patients presenting with unexplained cognitive changes, especially in the presence of vascular risk factors. Neuroimaging, particularly MRI, plays a pivotal role in diagnosis. Early identification and neurorehabilitation may improve cognitive outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Extensive corpus callosum infarction: an unusual presentation with unexpected neuroimaging

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月8日

查看全文
  • Ahmed Dahshan,
  • Ahmed Hamdy Youssef,
  • Mohammed Salah Eddin Siddig Ali,
  • Ahmed Mohamed Abdelmuty Nemr,
  • Mahmood Al Yahyaai,
  • Ali Mahmoud Ali Ayoub

摘要

Background

Corpus callosum infarctions are rare due to the region’s dual vascular supply and often present with nonspecific or atypical symptoms. The resulting diagnostic delay may impact management and outcomes.

Case presentation

We report a case of a female patient in her early sixties with a background of hypertension, diabetes mellitus, and stage IV chronic kidney disease. She presented with acute coronary syndrome and pulmonary edema. During hospitalization, she developed a new-onset cognitive decline, with a Mini-Mental State Examination (MMSE) score of 16/30. Neurological examination revealed no focal deficits but marked cognitive slowing. MRI of the brain showed acute infarction involving the entire corpus callosum. Workup for embolic sources and alternative diagnoses was unremarkable. The patient was managed conservatively due to comorbidities and gradually improved. Her MMSE improved to 24/30 at 1-week follow-up.

Conclusion

This case highlights the importance of considering corpus callosum infarction in patients presenting with unexplained cognitive changes, especially in the presence of vascular risk factors. Neuroimaging, particularly MRI, plays a pivotal role in diagnosis. Early identification and neurorehabilitation may improve cognitive outcomes.