Scholarlink

Background <p>Hypertensive disorders during pregnancy are a major global cause of maternal and neonatal mortality. Delivery remains the only effective management for eclampsia and severe preeclampsia (PE). Currently, the decision to deliver the baby prematurely is based on clinical manifestations and neurological examinations, but there is no objective tool to monitor cerebral involvement. Eclampsia presents with abroad spectrum of signs ranging from proteinuria and severe hypertension (HTN) to moderate or non-existent HTN without proteinuria with seizure or end orang damage. This study aims to use Digital electroencephalogram (DEEG) to monitor and track the progression of PE and eclampsia and correlate DEEG findings with clinical data. This case- control study was conducted at Ain Shams University Hospitals from August 2019 to August 2022. It included 35 patients consisting of (24 with PE and 11 with eclampsia), and 35 control subjects. All participants underwent a comprehensive medical history, clinical examination, and a 25-min DEEG.</p> Results <p>A 25-min DEEG was performed for both cases and controls.Among the cases, 14 (40%) showed abnormal DEEG findings such as focal activity and slow waves (9 eclampsia cases and 5 PE cases). No abnormalities were observed in the control group. In patients with PE and abnormal DEEG findings, systolic blood pressure (SBP) exceeded 160&#xa0;mmHg and diastolic blood pressure(DBP) exceeded 110&#xa0;mmHg, indicating that those with severe HTN are at higher risk of brain injury.</p> Conclusion <p>Abnormal DEEG patterns are more common in pregnant women with PE and eclampsia, indicating subclinical cerebral dysfunction that may predispose to seizures. These findings were more prominent in cases of severe PE, supporting the role of DEEG as a potential tool for early central nervous system (CNS) involvement detection.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Electroencephalographic study of preeclampsia and eclampsia patients in Egyptian women

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月10日

查看全文
  • Mahmoud Ahmed,
  • Mahmoud Hemeda,
  • Naglaa M.Elkhayat,
  • Ahmed Gaber,
  • Eman Mones

摘要

Background

Hypertensive disorders during pregnancy are a major global cause of maternal and neonatal mortality. Delivery remains the only effective management for eclampsia and severe preeclampsia (PE). Currently, the decision to deliver the baby prematurely is based on clinical manifestations and neurological examinations, but there is no objective tool to monitor cerebral involvement. Eclampsia presents with abroad spectrum of signs ranging from proteinuria and severe hypertension (HTN) to moderate or non-existent HTN without proteinuria with seizure or end orang damage. This study aims to use Digital electroencephalogram (DEEG) to monitor and track the progression of PE and eclampsia and correlate DEEG findings with clinical data. This case- control study was conducted at Ain Shams University Hospitals from August 2019 to August 2022. It included 35 patients consisting of (24 with PE and 11 with eclampsia), and 35 control subjects. All participants underwent a comprehensive medical history, clinical examination, and a 25-min DEEG.

Results

A 25-min DEEG was performed for both cases and controls.Among the cases, 14 (40%) showed abnormal DEEG findings such as focal activity and slow waves (9 eclampsia cases and 5 PE cases). No abnormalities were observed in the control group. In patients with PE and abnormal DEEG findings, systolic blood pressure (SBP) exceeded 160 mmHg and diastolic blood pressure(DBP) exceeded 110 mmHg, indicating that those with severe HTN are at higher risk of brain injury.

Conclusion

Abnormal DEEG patterns are more common in pregnant women with PE and eclampsia, indicating subclinical cerebral dysfunction that may predispose to seizures. These findings were more prominent in cases of severe PE, supporting the role of DEEG as a potential tool for early central nervous system (CNS) involvement detection.