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Background <p>Personality disorders are commonly found as co-morbid conditions among those undergoing treatment for substance-related disorders. In spite of the growing evidence for the correlation between substance-related disorders and personality disorders in general, it remains unclear to what extent specific personality disorders are uniquely associated with particular categories of substances.</p> Objectives <p>To investigate the association between personality disorders and choice of drug of abuse in an Egyptian sample of substance-dependent patients.</p> Methods <p>This investigation was conducted using a cross-sectional approach. It included 58 male patients, aged 18–55 years, seeking treatment for substance dependence at the outpatient clinic, Helwan University Hospital in Cairo, Egypt. Eligibility required meeting DSM-IV-TR diagnostic standards for opioid, sedative, or alcohol dependence and had been using the same substance predominantly over the last year. Urine screening tests confirmed the presence of only one substance. After obtaining informed consent, participants were assessed using the Arabic version of the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-IIP) to diagnose comorbid personality disorders.</p> Results <p>Regarding the prevalence of personality disorders among participants of 58 patients with substance use disorder, narcissistic personality disorder was the most prevalent disorder 37.9% (22 patients), followed by antisocial personality disorder 31% (18 patients), obsessive–compulsive disorder 24.1% (14 patients), and borderline personality disorder 22.4% (13 patients). Regarding association between personality disorders and choice of drug of abuse among participants, choice of heroin as drug of preference was significantly associated with presence of narcissistic and antisocial personality disorders, choice of alcohol was significantly associated with presence of obsessive–compulsive and paranoid personality disorders, while choosing benzodiazepine was significantly associated with dependent personality disorder.</p> Conclusions <p>This preliminary study identified significant associations between specific personality disorders and substance preference in treatment-seeking patients. Narcissistic and antisocial personality disorders were linked to heroin use, obsessive–compulsive and paranoid disorders to alcohol, and dependent personality disorder to benzodiazepine use. These findings should be interpreted cautiously due to the small sample size and male-only cohort, and further research with larger and more diverse samples is needed to validate and extend these results.</p>

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Personality disorders associated with alcohol, heroin and sedative use disorders in an Egyptian sample: a preliminary study

  • 期刊论文

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  • 发表日期：

    2025年10月6日

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  • Haytham M. Hasan,
  • Amany H. El Rasheed,
  • Mostafa Bastawy,
  • Mohammed M. Elhamshary,
  • Marwa M. Ghanem

摘要

Background

Personality disorders are commonly found as co-morbid conditions among those undergoing treatment for substance-related disorders. In spite of the growing evidence for the correlation between substance-related disorders and personality disorders in general, it remains unclear to what extent specific personality disorders are uniquely associated with particular categories of substances.

Objectives

To investigate the association between personality disorders and choice of drug of abuse in an Egyptian sample of substance-dependent patients.

Methods

This investigation was conducted using a cross-sectional approach. It included 58 male patients, aged 18–55 years, seeking treatment for substance dependence at the outpatient clinic, Helwan University Hospital in Cairo, Egypt. Eligibility required meeting DSM-IV-TR diagnostic standards for opioid, sedative, or alcohol dependence and had been using the same substance predominantly over the last year. Urine screening tests confirmed the presence of only one substance. After obtaining informed consent, participants were assessed using the Arabic version of the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-IIP) to diagnose comorbid personality disorders.

Results

Regarding the prevalence of personality disorders among participants of 58 patients with substance use disorder, narcissistic personality disorder was the most prevalent disorder 37.9% (22 patients), followed by antisocial personality disorder 31% (18 patients), obsessive–compulsive disorder 24.1% (14 patients), and borderline personality disorder 22.4% (13 patients). Regarding association between personality disorders and choice of drug of abuse among participants, choice of heroin as drug of preference was significantly associated with presence of narcissistic and antisocial personality disorders, choice of alcohol was significantly associated with presence of obsessive–compulsive and paranoid personality disorders, while choosing benzodiazepine was significantly associated with dependent personality disorder.

Conclusions

This preliminary study identified significant associations between specific personality disorders and substance preference in treatment-seeking patients. Narcissistic and antisocial personality disorders were linked to heroin use, obsessive–compulsive and paranoid disorders to alcohol, and dependent personality disorder to benzodiazepine use. These findings should be interpreted cautiously due to the small sample size and male-only cohort, and further research with larger and more diverse samples is needed to validate and extend these results.