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<p>Gastrointestinal stromal tumors (GISTs) are rare stromal neoplasms that predominantly arise in the gastrointestinal tract. <sup>18</sup>F-AlF-NOTA-octreotide (<sup>18</sup>F-OC) is a novel molecularly targeted probe that specifically binds to tumors expressing somatostatin receptors. A 45-year-old male patient underwent <sup>18</sup>F-OC PET/CT due to clinical suspicion of a pancreatic neuroendocrine tumor. Imaging revealed a mass with increased <sup>18</sup>F-OC uptake inferior to the pancreatic head. The patient subsequently underwent surgical resection, and histopathological assessment confirmed a low-risk gastrointestinal stromal tumor.</p>

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Uptake of 18F-AlF-NOTA-octreotide PET/CT in gastrointestinal stromal tumors

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月24日

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  • Xiaodan Xu,
  • Guanyun Wang,
  • Xiaojun Zhang,
  • Ruimin Wang,
  • Guangyu Ma

摘要

Gastrointestinal stromal tumors (GISTs) are rare stromal neoplasms that predominantly arise in the gastrointestinal tract. 18F-AlF-NOTA-octreotide (18F-OC) is a novel molecularly targeted probe that specifically binds to tumors expressing somatostatin receptors. A 45-year-old male patient underwent 18F-OC PET/CT due to clinical suspicion of a pancreatic neuroendocrine tumor. Imaging revealed a mass with increased 18F-OC uptake inferior to the pancreatic head. The patient subsequently underwent surgical resection, and histopathological assessment confirmed a low-risk gastrointestinal stromal tumor.