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Background <p>Sjögren disease (SjD) and non-Sjögren <i>sicca</i> (nSS) individuals exhibit symptoms of oral dryness. However, studies investigating factors influencing oral health-related quality of life (OHRQoL) in these groups remain scarce.</p> Purpose <p>To evaluate OHRQoL in SjD and nSS patients and identify factors influencing its perception.</p> Methods <p>A cross-sectional study was conducted. The short version of the Oral Health Impact Profile-14 (OHIP-14) questionnaire was administered. Bivariate analyses were performed to examine associations between independent variables and OHRQoL. Statistical significance was set at <i>p</i> &lt; 0.05.</p> Results <p>A total of 116 individuals were evaluated, including 79 with SjD and 37 with nSS. Hyposalivation was more frequent in SjD (55.7%) than in nSS (27.0%). The median overall OHIP-14 score was higher in nSS (30.0) than in SjD (22.0) (<i>p</i> = 0.027), indicating poorer OHRQoL among nSS individuals. In SjD, hyposalivation significantly worsened OHIP-14 across five domains, whereas this association was absent in nSS. A negative correlation between unstimulated salivary flow rate and clinical oral dryness score, and a positive correlation between decayed, missing, and filled teeth index and OHIP-14, were observed only in nSS.</p> Conclusion <p>OHRQoL impairment was greater in nSS, but salivary dysfunction exerted stronger effects in SjD, underscoring distinct determinants in <i>sicca</i> conditions.</p>

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Oral health-related quality of life in Sjögren disease and non-Sjögren sicca: a cross-sectional study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月14日

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  • Laiz Fernandes Mendes Nunes,
  • Lucas Tadeu Ferreira Gomes,
  • Fernanda Aragão Felix,
  • José Alcides Almeida de Arruda,
  • Clarice Klem de Castro Pinheiro,
  • Lucas Guimarães Abreu,
  • Benjamin P. J. Fournier,
  • Leandro Augusto Tanure,
  • Débora Cerqueira Calderaro,
  • Maurício Augusto Aquino de Castro,
  • Tarcília Aparecida Silva,
  • Sílvia Ferreira de Sousa

摘要

Background

Sjögren disease (SjD) and non-Sjögren sicca (nSS) individuals exhibit symptoms of oral dryness. However, studies investigating factors influencing oral health-related quality of life (OHRQoL) in these groups remain scarce.

Purpose

To evaluate OHRQoL in SjD and nSS patients and identify factors influencing its perception.

Methods

A cross-sectional study was conducted. The short version of the Oral Health Impact Profile-14 (OHIP-14) questionnaire was administered. Bivariate analyses were performed to examine associations between independent variables and OHRQoL. Statistical significance was set at p < 0.05.

Results

A total of 116 individuals were evaluated, including 79 with SjD and 37 with nSS. Hyposalivation was more frequent in SjD (55.7%) than in nSS (27.0%). The median overall OHIP-14 score was higher in nSS (30.0) than in SjD (22.0) (p = 0.027), indicating poorer OHRQoL among nSS individuals. In SjD, hyposalivation significantly worsened OHIP-14 across five domains, whereas this association was absent in nSS. A negative correlation between unstimulated salivary flow rate and clinical oral dryness score, and a positive correlation between decayed, missing, and filled teeth index and OHIP-14, were observed only in nSS.

Conclusion

OHRQoL impairment was greater in nSS, but salivary dysfunction exerted stronger effects in SjD, underscoring distinct determinants in sicca conditions.