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Purpose <p>To assess whether the number of nights utilised for initiation and titration of continuous positive airway pressure (CPAP) therapy (and/or the use of an additional ‘parent night’) for patients attending the Queensland Children’s Hospital (QCH) Sleep Unit was an independent predictor of:</p> <p>1.&#xa0;Subsequent adherence to therapy (primary outcome)</p> <p>2.&#xa0;Amount of readjustment of the therapy at subsequent visit</p> Methods <p>A retrospective review of children initiated on CPAP from 2015 to 2022 was performed using existing data extracted from the QCH Sleep Unit records. Children aged &lt;18 years at commencement of CPAP were included. Demographic data, number of nights for initiation, change in CPAP prescription at next titration study, and adherence data were included in the study.</p> Results <p>From 376 patients assessed<b>,</b> results demonstrated that single night initiation (p-value 0.03), later year of initiation (p-value 0.03), and comorbid neurodisability diagnosis (p-value 0.03) predicted non-adherence on univariable analysis, but these factors did not retain statistical significance in multivariable modelling. Parent nights were more likely in those receiving multi-night titration studies (30% vs 19%), though did not have a statistically significant impact on adherence. None of the factors assessed were significantly associated with changes to CPAP prescription at the subsequent titration sleep studies.</p> Conclusion <p>Children who underwent single night CPAP initiation, had a later year of commencing CPAP and/or who had a neurodisability diagnosis were more often non-adherent to the prescribed treatment on the basis of objective data downloaded from their CPAP machine.</p>

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How many nights is just right? Effect of number of nights spent initiating continuous positive airway pressure in the paediatric sleep laboratory on treatment adherence

  • 期刊论文

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  • 发表日期：

    2025年12月28日

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  • Anna Windress,
  • Andrew Collaro,
  • Ai Xin Chew,
  • Alice Wilson,
  • Marie-Josee Leclerc,
  • Jasneek Chawla,
  • Ajay Kevat

摘要

Purpose

To assess whether the number of nights utilised for initiation and titration of continuous positive airway pressure (CPAP) therapy (and/or the use of an additional ‘parent night’) for patients attending the Queensland Children’s Hospital (QCH) Sleep Unit was an independent predictor of:

1. Subsequent adherence to therapy (primary outcome)

2. Amount of readjustment of the therapy at subsequent visit

Methods

A retrospective review of children initiated on CPAP from 2015 to 2022 was performed using existing data extracted from the QCH Sleep Unit records. Children aged <18 years at commencement of CPAP were included. Demographic data, number of nights for initiation, change in CPAP prescription at next titration study, and adherence data were included in the study.

Results

From 376 patients assessed, results demonstrated that single night initiation (p-value 0.03), later year of initiation (p-value 0.03), and comorbid neurodisability diagnosis (p-value 0.03) predicted non-adherence on univariable analysis, but these factors did not retain statistical significance in multivariable modelling. Parent nights were more likely in those receiving multi-night titration studies (30% vs 19%), though did not have a statistically significant impact on adherence. None of the factors assessed were significantly associated with changes to CPAP prescription at the subsequent titration sleep studies.

Conclusion

Children who underwent single night CPAP initiation, had a later year of commencing CPAP and/or who had a neurodisability diagnosis were more often non-adherent to the prescribed treatment on the basis of objective data downloaded from their CPAP machine.