Scholarlink

Background <p>Native polyetheretherketone (PEEK) exhibits limitations in mechanical strength, radiographic visibility, and bioactivity for craniomaxillofacial (CMF) applications. This proof-of-concept study establishes the feasibility of point-of-care (POC) manufacturing for three functionalized PEEK composites for patient-specific CMF implants using a high-temperature material extrusion (MEX) system, with application-specific material selection to overcome these limitations.</p> Methods <p>Carbon fiber-reinforced PEEK (CFR-PEEK), barium sulfate-filled PEEK (BaSO₄-PEEK), and biphasic calcium phosphate-filled PEEK (BCP-PEEK) were fabricated into patient-specific mandibular reconstruction plates, orbital floor implants, and chin augmentation implants, respectively. Manufacturing success rates, dimensional accuracy via root mean square (RMS) deviation analysis, post-sterilization dimensional stability, and layer adhesion quality were evaluated.</p> Results <p>Fabrication success rates of 100% (CFR-PEEK), 100% (BaSO₄-PEEK), and 85.7% (BCP-PEEK) were achieved. Dimensional accuracy analysis revealed RMS deviations of 0.16–0.29&#xa0;mm between 3D-printed implants and original designs, within clinically acceptable ranges. Post-sterilization dimensional changes were minimal (RMS 0.05–0.07&#xa0;mm). Complete layer adhesion was demonstrated across all materials, with no delamination or cracking observed.</p> Conclusion <p>These findings establish the manufacturing viability of POC fabrication of application-matched PEEK composites for patient-specific CMF implants, enhancing mechanical, radiographic, and bioactive properties whilst maintaining geometric customization.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Application-matched point-of-care 3D printing of functionalized polyetheretherketone (PEEK) composites for patient-specific craniomaxillofacial implants

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月24日

查看全文
  • Jokin Zubizarreta Oteiza,
  • Yannick Krieger,
  • Daniel Seiler,
  • Florian M. Thieringer,
  • Neha Sharma

摘要

Background

Native polyetheretherketone (PEEK) exhibits limitations in mechanical strength, radiographic visibility, and bioactivity for craniomaxillofacial (CMF) applications. This proof-of-concept study establishes the feasibility of point-of-care (POC) manufacturing for three functionalized PEEK composites for patient-specific CMF implants using a high-temperature material extrusion (MEX) system, with application-specific material selection to overcome these limitations.

Methods

Carbon fiber-reinforced PEEK (CFR-PEEK), barium sulfate-filled PEEK (BaSO₄-PEEK), and biphasic calcium phosphate-filled PEEK (BCP-PEEK) were fabricated into patient-specific mandibular reconstruction plates, orbital floor implants, and chin augmentation implants, respectively. Manufacturing success rates, dimensional accuracy via root mean square (RMS) deviation analysis, post-sterilization dimensional stability, and layer adhesion quality were evaluated.

Results

Fabrication success rates of 100% (CFR-PEEK), 100% (BaSO₄-PEEK), and 85.7% (BCP-PEEK) were achieved. Dimensional accuracy analysis revealed RMS deviations of 0.16–0.29 mm between 3D-printed implants and original designs, within clinically acceptable ranges. Post-sterilization dimensional changes were minimal (RMS 0.05–0.07 mm). Complete layer adhesion was demonstrated across all materials, with no delamination or cracking observed.

Conclusion

These findings establish the manufacturing viability of POC fabrication of application-matched PEEK composites for patient-specific CMF implants, enhancing mechanical, radiographic, and bioactive properties whilst maintaining geometric customization.