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Objectives <p>This study examined the frequency of vitamin D insufficiency, its correlation with metabolic syndrome (MetS), and its constituents among Jordanian females.</p> Methods <p>A cross-sectional study of 428 Jordanian females between 18 and 65 years. The Adult Treatment Panel III (ATPIII) criteria were used to identify females with MetS. Vitamin D3 levels, anthropometric measurements, and biochemical parameters were evaluated. In terms of serum 25(OH)D concentration, the female subjects were divided into three groups: deficient (&lt; 20 ng/mL), insufficient (20–29 ng/mL), and sufficient (≥ 30 ng/mL).</p> Results <p>Mean serum 25(OH)D was 20.66 ± 11.32 ng/ml and 21.03 ± 12.69 in females with and without MetS, respectively (<i>p</i> = 0.743). The prevalence of vitamin D deficiency and MetS in the study population was 54.4% and 55.8%, respectively. Serum 25(OH)D levels showed no significant correlation with components of MetS. Among the five elements, high triglyceride (TG) levels are the most prevalent, occurring in 88.8% of cases.</p> Conclusions <p>The findings indicate a high prevalence of vitamin D deficiency among patients with MetS in Jordan. Contrary to previous studies, we found no correlation between serum 25(OH)D status and MetS in a sample of Jordanian females. Additional prospective studies are required to ascertain the potential impact of vitamin D on the progression of MetS.</p>

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The relationship between vitamin D serum levels and metabolic syndrome and its components among Jordanian females: a cross-sectional study

  • 期刊论文

  • 发表日期：

    2025年11月5日

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  • Buthaina Alkhatib,
  • Huda M. Al Hourani,
  • Lana M. Agraib

摘要

Objectives

This study examined the frequency of vitamin D insufficiency, its correlation with metabolic syndrome (MetS), and its constituents among Jordanian females.

Methods

A cross-sectional study of 428 Jordanian females between 18 and 65 years. The Adult Treatment Panel III (ATPIII) criteria were used to identify females with MetS. Vitamin D3 levels, anthropometric measurements, and biochemical parameters were evaluated. In terms of serum 25(OH)D concentration, the female subjects were divided into three groups: deficient (< 20 ng/mL), insufficient (20–29 ng/mL), and sufficient (≥ 30 ng/mL).

Results

Mean serum 25(OH)D was 20.66 ± 11.32 ng/ml and 21.03 ± 12.69 in females with and without MetS, respectively (p = 0.743). The prevalence of vitamin D deficiency and MetS in the study population was 54.4% and 55.8%, respectively. Serum 25(OH)D levels showed no significant correlation with components of MetS. Among the five elements, high triglyceride (TG) levels are the most prevalent, occurring in 88.8% of cases.

Conclusions

The findings indicate a high prevalence of vitamin D deficiency among patients with MetS in Jordan. Contrary to previous studies, we found no correlation between serum 25(OH)D status and MetS in a sample of Jordanian females. Additional prospective studies are required to ascertain the potential impact of vitamin D on the progression of MetS.