Scholarlink

Background <p>Behçet’s disease (BD) is a multisystem inflammatory disease of unknown etiology characterized by recurrent acute flares. Vascular lesions can present major challenges for transplantation. Solid organ transplantation in patients with BD requires careful assessment of peripheral vascular lesions.</p> Case presentation <p>A 67-year-old man with BD underwent ABO-incompatible, donor-specific antibody-negative, living-donor preemptive kidney transplantation (KTx). Because of bilateral external iliac vein thrombosis, the patient received intensified anticoagulation with warfarin for 6&#xa0;months, and an inferior vena cava filter was placed prior to KTx. Postoperatively, he experienced complications, including two aneurysm formations requiring stent placement; all were managed successfully, and his allograft kidney function remained stable.</p> Conclusions <p>KTx in patients with BD can be performed safely when BD activity is appropriately assessed and when adequate treatment is administered preoperatively and maintained throughout the post-KTx period.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Safety management of kidney transplantation in patients with Behçet’s disease: A case report with literature review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月10日

查看全文
  • Yuki Nemoto,
  • Kohei Unagami,
  • Hiroki Shirakawa,
  • Ayaka Saitoh,
  • Daigo Okada,
  • Takafumi Yagisawa,
  • Miyuki Furusawa,
  • Toshihito Hirai,
  • Kazuya Omoto,
  • Tomokazu Shimizu,
  • Junichi Hoshino,
  • Hideki Ishida,
  • Toshio Takagi

摘要

Background

Behçet’s disease (BD) is a multisystem inflammatory disease of unknown etiology characterized by recurrent acute flares. Vascular lesions can present major challenges for transplantation. Solid organ transplantation in patients with BD requires careful assessment of peripheral vascular lesions.

Case presentation

A 67-year-old man with BD underwent ABO-incompatible, donor-specific antibody-negative, living-donor preemptive kidney transplantation (KTx). Because of bilateral external iliac vein thrombosis, the patient received intensified anticoagulation with warfarin for 6 months, and an inferior vena cava filter was placed prior to KTx. Postoperatively, he experienced complications, including two aneurysm formations requiring stent placement; all were managed successfully, and his allograft kidney function remained stable.

Conclusions

KTx in patients with BD can be performed safely when BD activity is appropriately assessed and when adequate treatment is administered preoperatively and maintained throughout the post-KTx period.