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Background <p>The study aimed to assess the pooled prevalence of undernutrition and its associated factors among HIV-positive adults in Ethiopia.</p> Methods <p>Intensive searches were conducted using PubMed, EMBASE (Elsevier), Cochrane, and other electronic databases, including ScienceDirect, African Journal Online (AJOL), Google Scholar, and gray literature. The protocol is registered and accessible at <a href="https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42023403023">https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42023403023</a>.</p> Data synthesis/findings <p>The study found that the pooled prevalence of 26.70% (95% CI: 21.31%, 32.10%) of HIV-positive patients in Ethiopia are undernourished. Undernutrition is associated with opportunistic infections (OIs) (OR: 3.50, 95% CI 1.78–5.22), advanced WHO clinical stage II or higher (OR: 2.92, 95% CI 1.09–4.74), a cluster differentiation (CD4) count of fewer than 200 cells (OR: 3.10, 95% CI 1.42–4.78), and food insecurity (OR: 3.62, 95% CI 1.46–5.79).</p> Conclusion <p>The Ethiopian HIV-positive population experiences significant undernutrition, which is influenced by factors such as OIs, advanced disease stage, CD4 levels, and food insecurity. More research is needed to verify the underlying issues.</p>

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Prevalence and associated factors of undernutrition among adults living with HIV in ethiopia: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月14日

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  • Amare Admasu,
  • Takele Tadesse,
  • Amene Abebe,
  • Eskinder Wolka

摘要

Background

The study aimed to assess the pooled prevalence of undernutrition and its associated factors among HIV-positive adults in Ethiopia.

Methods

Intensive searches were conducted using PubMed, EMBASE (Elsevier), Cochrane, and other electronic databases, including ScienceDirect, African Journal Online (AJOL), Google Scholar, and gray literature. The protocol is registered and accessible at https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42023403023.

Data synthesis/findings

The study found that the pooled prevalence of 26.70% (95% CI: 21.31%, 32.10%) of HIV-positive patients in Ethiopia are undernourished. Undernutrition is associated with opportunistic infections (OIs) (OR: 3.50, 95% CI 1.78–5.22), advanced WHO clinical stage II or higher (OR: 2.92, 95% CI 1.09–4.74), a cluster differentiation (CD4) count of fewer than 200 cells (OR: 3.10, 95% CI 1.42–4.78), and food insecurity (OR: 3.62, 95% CI 1.46–5.79).

Conclusion

The Ethiopian HIV-positive population experiences significant undernutrition, which is influenced by factors such as OIs, advanced disease stage, CD4 levels, and food insecurity. More research is needed to verify the underlying issues.