Scholarlink

Background <p>In insulin treatment for type 1 diabetes, intermittent scanning continuous glucose monitoring (isCGM: FreeStyle® Libre), in which a sensor is adhered to the skin, is often used to monitor blood glucose fluctuations and manage glucose levels. Zinc-deficient skin is reportedly more susceptible to primary irritant rashes. This study investigated whether zinc deficiency is associated with a history of contact dermatitis caused by isCGM in patients with type 1 diabetes.</p> Methods <p>The subjects comprised 55 patients (23 men, 32 women, age 57.9 ± 17.6&#xa0;years) with type 1 diabetes who were outpatients at our department and had a history of isCGM use. We examined the history of contact dermatitis due to isCGM in relation to serum zinc concentration.</p> Results <p>Serum zinc was significantly lower in those with history of contact dermatitis (23 subjects) compared to those without (32 subjects) (<i>P</i> = 0.033). History of contact dermatitis due to isCGM was negatively associated with both age (β =  − 0.266, <i>P</i> = 0.040) and zinc deficiency category (β =  − 0.315, <i>P</i> = 0.017).</p> Conclusions <p>For people undergoing treatment for type 1 diabetes for whom skin problems caused by isCGM are a barrier to glucose management, screening of serum zinc concentration may be important.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Serum zinc concentration and history of isCGM contact dermatitis in type 1 diabetes

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月17日

查看全文
  • Mitsunobu Kubota,
  • Shizuka Matsuda,
  • Mimu Matsuda,
  • Shinji Maeda,
  • Sayo Yoshiyama

摘要

Background

In insulin treatment for type 1 diabetes, intermittent scanning continuous glucose monitoring (isCGM: FreeStyle® Libre), in which a sensor is adhered to the skin, is often used to monitor blood glucose fluctuations and manage glucose levels. Zinc-deficient skin is reportedly more susceptible to primary irritant rashes. This study investigated whether zinc deficiency is associated with a history of contact dermatitis caused by isCGM in patients with type 1 diabetes.

Methods

The subjects comprised 55 patients (23 men, 32 women, age 57.9 ± 17.6 years) with type 1 diabetes who were outpatients at our department and had a history of isCGM use. We examined the history of contact dermatitis due to isCGM in relation to serum zinc concentration.

Results

Serum zinc was significantly lower in those with history of contact dermatitis (23 subjects) compared to those without (32 subjects) (P = 0.033). History of contact dermatitis due to isCGM was negatively associated with both age (β =  − 0.266, P = 0.040) and zinc deficiency category (β =  − 0.315, P = 0.017).

Conclusions

For people undergoing treatment for type 1 diabetes for whom skin problems caused by isCGM are a barrier to glucose management, screening of serum zinc concentration may be important.