Regression of cardiac angiosarcoma in a 17-year-old: a percutaneous biopsy effect

期刊论文
出版模式：

开放获取
发表日期：

2024年7月23日

查看全文

Noor Sharrack,
Martine Parent,
Christopher Lethaby,
Ulrich Rosendahl,
Alexander R Lyon,
Maryum Farooq,
Haqeel Jamil,
John P. Greenwood,
Sven Plein,
Ananth Kidambi

摘要

Background

Cardiac angiosarcoma is a very rare and aggressive primary cardiac tumor associated with poor prognosis. Diagnosis is often delayed due to non-specific symptoms, with most cases involving metastases at the time of diagnosis. We describe a unique case of apparent tumor regression of cardiac angiosarcoma post percutaneous biopsy.

Case Presentation

A young male was admitted with suspected pericarditis. Echocardiogram revealed a pericardial mass. Cardiovascular magnetic resonance (CMR) suggested primary cardiac malignancy. Percutaneous biopsy was inconclusive, with subsequent CMR demonstrating apparent tumor regression. Interval imaging revealed further tumor growth, and surgical biopsy revealed primary cardiac angiosarcoma (PCAS). Causes of tumor regression following percutaneous biopsy are discussed.

Conclusions

Cases of suspected primary cardiac malignancy require careful follow up with serial multimodality imaging. Percutaneous biopsy effects should be considered in cases of tumor regression, and serial imaging should be planned afterwards.