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Purpose <p>To discuss the recent evidence that Janus kinase (JAK) inhibitors can cause viral retinitis.</p> Methods <p>A commentary on the case report in this issue and a review of cases in the literature.</p> Results <p>A total of 6 cases have now been reported of cytomegalovirus retinitis associated with Jak inhibitors. Additionally, there was a case of bilateral toxoplasma retinitis and a case of herpetic scleritis.</p> Discussion <p>It is important to be aware of the potential blinding complications associated with JAK inhibitors and if the patient complains of acute vision loss and/or floaters, the patient should be emergently referred to a retina specialist.</p>

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Infectious retinitis associated with JAK inhibitors: the ongoing duality of JAK inhibitors

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月6日

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  • Jose S. Pulido,
  • Fukutaro Mano,
  • Marcello Casella,
  • Susumu Ishida

摘要

Purpose

To discuss the recent evidence that Janus kinase (JAK) inhibitors can cause viral retinitis.

Methods

A commentary on the case report in this issue and a review of cases in the literature.

Results

A total of 6 cases have now been reported of cytomegalovirus retinitis associated with Jak inhibitors. Additionally, there was a case of bilateral toxoplasma retinitis and a case of herpetic scleritis.

Discussion

It is important to be aware of the potential blinding complications associated with JAK inhibitors and if the patient complains of acute vision loss and/or floaters, the patient should be emergently referred to a retina specialist.