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Purpose <p>Persistent optic disc bleeding during pars plana vitrectomy (PPV) is difficult to manage. This study aims to explore the use of fibrin glue as a novel agent to achieve hemostasis in such eyes.</p> Methods <p>Interventional case series of patients with vitreous hemorrhage (VH) or tractional retinal detachment (TRD) due to proliferative diabetic retinopathy, retinal vein occlusion or retinal vasculitis, in whom fibrin glue was used intraoperatively for hemostasis. All the patients were followed up for 1 month.</p> Results <p>14 eyes of 14 patients were included, of which 12 (85.7%) were male with mean age of 52 years. Surgery was performed in 10 eyes (71.4%) for VH and 4 eyes (28.6%) for TRD. The mean best corrected visual acuity (BCVA) improved from 1.33±0.53 Logarithm of the Minimum Angle of Resolution (logMAR) (20/428), to 0.42± 0.35 logMAR (20/53) 1 month after surgery (<i>P</i> = 0.002), 0.43± 0.32 logMAR (20/54) 3 months after surgery (<i>p</i> = 0.003) and 0.36±0.34 logMAR (20/46) at a mean of 7 months (<i>p</i> = 0.002) after the surgery. Post operative vitreous cavity hemorrhage occurred in 1 eye (7.1%), which did not require a repeat surgery.</p> Conclusions <p>This report demonstrates the efficacy of fibrin glue used during vitrectomy in controlling persistent optic disc hemorrhage in a cohort of diverse etiologies.</p>

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Clinical outcomes of fibrin glue assisted hemostasis in persistent intraoperative optic disc bleeding

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月6日

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  • Saarang Hansraj,
  • Thirumalesh MB,
  • Brijesh Takkar,
  • Vivek Pravin Dave,
  • Ritesh Narula,
  • Srishti Raksheeth Ramamurthy,
  • Mudit Tyagi

摘要

Purpose

Persistent optic disc bleeding during pars plana vitrectomy (PPV) is difficult to manage. This study aims to explore the use of fibrin glue as a novel agent to achieve hemostasis in such eyes.

Methods

Interventional case series of patients with vitreous hemorrhage (VH) or tractional retinal detachment (TRD) due to proliferative diabetic retinopathy, retinal vein occlusion or retinal vasculitis, in whom fibrin glue was used intraoperatively for hemostasis. All the patients were followed up for 1 month.

Results

14 eyes of 14 patients were included, of which 12 (85.7%) were male with mean age of 52 years. Surgery was performed in 10 eyes (71.4%) for VH and 4 eyes (28.6%) for TRD. The mean best corrected visual acuity (BCVA) improved from 1.33±0.53 Logarithm of the Minimum Angle of Resolution (logMAR) (20/428), to 0.42± 0.35 logMAR (20/53) 1 month after surgery (P = 0.002), 0.43± 0.32 logMAR (20/54) 3 months after surgery (p = 0.003) and 0.36±0.34 logMAR (20/46) at a mean of 7 months (p = 0.002) after the surgery. Post operative vitreous cavity hemorrhage occurred in 1 eye (7.1%), which did not require a repeat surgery.

Conclusions

This report demonstrates the efficacy of fibrin glue used during vitrectomy in controlling persistent optic disc hemorrhage in a cohort of diverse etiologies.