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Background <p>Given the high prevalence and severe consequences of suicidal ideation (SI) in adolescents, it is critical to identify multidimensional predictors of the illness. This study aimed to investigate the physiological, psychological, and sociological factors that influence SI in adolescents with first-episode depressive disorder.</p> Methods <p>The study was recruited through convenience sampling. Data were collected using self-designed questionnaires, the Hamilton Depression Scale 24-item, the Hamilton Anxiety Scale, and the Simplified Coping Style Questionnaire. Thyroid function, cortisol, lipids, and event-related potential were measured in the participants. All independent variables were included in the model for logistic regression. Statistical analysis of data was done using SPSS version 25.0.</p> Results <p>The present study was for the inclusion of 150 adolescents who presented with first-episode depressive disorder, of whom 96 (64.00%) had SI. Females and older adolescents were more prone to SI. Depressive symptoms, anxiety symptoms, negative coping styles, total cholesterol levels, and the latency of P3a and P3b were positively correlated with SI. Positive coping style, N2 amplitude, and SI were negatively correlated.</p> Conclusions <p>SI in Chinese adolescents with first-episode depressive disorder demonstrates a multifactorial relationship, involving physiological, psychological, and sociological factors. It is necessary to conduct multidomain, comprehensive assessments and develop intervention strategies.</p>

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Factors influencing suicidal ideation in Chinese adolescents with first-episode depressive disorder: a cross-sectional study

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年1月22日

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  • Yang Zhang,
  • Xingbo Suo,
  • Jingjing Xu,
  • Wu Li,
  • Xinqi Wang,
  • Wangwang Xu,
  • Liangke Pan,
  • Jingxue Wang,
  • Jin Gao

摘要

Background

Given the high prevalence and severe consequences of suicidal ideation (SI) in adolescents, it is critical to identify multidimensional predictors of the illness. This study aimed to investigate the physiological, psychological, and sociological factors that influence SI in adolescents with first-episode depressive disorder.

Methods

The study was recruited through convenience sampling. Data were collected using self-designed questionnaires, the Hamilton Depression Scale 24-item, the Hamilton Anxiety Scale, and the Simplified Coping Style Questionnaire. Thyroid function, cortisol, lipids, and event-related potential were measured in the participants. All independent variables were included in the model for logistic regression. Statistical analysis of data was done using SPSS version 25.0.

Results

The present study was for the inclusion of 150 adolescents who presented with first-episode depressive disorder, of whom 96 (64.00%) had SI. Females and older adolescents were more prone to SI. Depressive symptoms, anxiety symptoms, negative coping styles, total cholesterol levels, and the latency of P3a and P3b were positively correlated with SI. Positive coping style, N2 amplitude, and SI were negatively correlated.

Conclusions

SI in Chinese adolescents with first-episode depressive disorder demonstrates a multifactorial relationship, involving physiological, psychological, and sociological factors. It is necessary to conduct multidomain, comprehensive assessments and develop intervention strategies.