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Background <p>Physical activity (PA) is crucial for the prevention and management of chronic diseases and may be associated with cognitive impairment. This study investigated the longitudinal relationship between PA from different parameters (e.g., frequency, duration, intensity, and volume) and the incidence of cognitive impairment in middle-aged and older adults.</p> Methods <p>Data were derived from the China Health and Retirement Longitudinal Study (2011–2015). A total of 891 adults aged 45 and older were included in this study. Cognitive function was assessed using the Telephone Interview for Cognitive Status criteria, focused on episodic memory and executive function. We categorized participants into normal cognition and cognitive impairment groups. Self-reported PA information including frequency, duration, intensity, and volume was collected through a representative survey. Poisson regression analysis was employed to explore the relationship between PA parameters and the incidence of cognitive impairment over four years.</p> Results <p>Engaging in moderate or light PA (MPA or LPA) at least three days per week, and vigorous PA (VPA) one to two days per week, was associated with a reduced incidence of cognitive impairment. Additionally, spending 30–119&#xa0;min per day or 150&#xa0;min per week or more on any PA intensity was linked to lower cognitive impairment prevalence. Sensitivity analysis, excluding individuals with neurological, mental, or memory impairments, confirmed these findings.</p> Conclusions <p>The findings highlight that the frequency, duration, and volume of VPA, MPA, or LPA are linked to the incidence of cognitive impairment. Regular PA may reduce the risk of cognitive impairment in middle-aged and older adults.</p>

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Relationship between different physical activity parameters and cognitive impairment in middle-aged and older adults: insights from a 4-year longitudinal study

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  • 发表日期：

    2025年3月19日

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  • Dongxue Liu,
  • Yihan Pan,
  • Jin Wang,
  • Shaoshuai Shen,
  • Xiaoguang Zhao

摘要

Background

Physical activity (PA) is crucial for the prevention and management of chronic diseases and may be associated with cognitive impairment. This study investigated the longitudinal relationship between PA from different parameters (e.g., frequency, duration, intensity, and volume) and the incidence of cognitive impairment in middle-aged and older adults.

Methods

Data were derived from the China Health and Retirement Longitudinal Study (2011–2015). A total of 891 adults aged 45 and older were included in this study. Cognitive function was assessed using the Telephone Interview for Cognitive Status criteria, focused on episodic memory and executive function. We categorized participants into normal cognition and cognitive impairment groups. Self-reported PA information including frequency, duration, intensity, and volume was collected through a representative survey. Poisson regression analysis was employed to explore the relationship between PA parameters and the incidence of cognitive impairment over four years.

Results

Engaging in moderate or light PA (MPA or LPA) at least three days per week, and vigorous PA (VPA) one to two days per week, was associated with a reduced incidence of cognitive impairment. Additionally, spending 30–119 min per day or 150 min per week or more on any PA intensity was linked to lower cognitive impairment prevalence. Sensitivity analysis, excluding individuals with neurological, mental, or memory impairments, confirmed these findings.

Conclusions

The findings highlight that the frequency, duration, and volume of VPA, MPA, or LPA are linked to the incidence of cognitive impairment. Regular PA may reduce the risk of cognitive impairment in middle-aged and older adults.