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Objective <p>Although various surgical approaches exist for superior mediastinal lymph node dissection in thyroid cancer, each technique has significant limitations. We present a novel surgical approach via the lateral cervical route that provides an alternative for thyroid cancer patients requiring this procedure.</p> Methods <p>We conducted a retrospective analysis on patients who underwent superior mediastinal lymph node dissection (SMLND) via the lateral cervical approach at an academic tertiary care center between June 2023 and December 2024. Surgical safety, efficacy, and short-term outcomes were evaluated.</p> Results <p>Our cohort consisted of 21 patients who successfully underwent superior mediastinal lymph node dissection via the lateral cervical approach without severe intraoperative complications. The mean operative time was 153.14 ± 37.52&#xa0;min, and the average intraoperative blood loss was 54.05 ± 18.84&#xa0;mL. No in-hospital deaths or uncontrollable intraoperative hemorrhages were observed. The mean postoperative hospital stay was 5.67 ± 0.91&#xa0;days. Postoperative complications included chylous leakage in 3 cases and hoarseness in 2 cases. All patients achieved macroscopically complete resection; the average number of superior mediastinal lymph nodes dissected was 7.86 ± 3.12. Follow-up at 3–6&#xa0;months revealed no abnormal elevation of thyroglobulin levels or imaging evidence of recurrent lymphadenopathy.</p> Conclusion <p>Our results suggest that this novel lateral cervical approach for SMLND is both safe and effective, offering an alternative option for surgeons managing this condition.</p> <p><i>Clinical Trial Information </i>This study was registered on the Clinical Trials Registry (NCT06793579) on January 21, 2025.</p>

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Lateral cervical approach for superior mediastinal lymph node dissection in thyroid cancer: a novel surgical technique

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月8日

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  • Cunye Yan,
  • Shaodong Hou,
  • Hongbiao Mo,
  • Zeyi Zhou,
  • Chenyu Sun,
  • Mi Tang,
  • Junle Wu,
  • Li Liu,
  • Wen Chen,
  • Junlei Li,
  • Yiceng Sun,
  • Fan Zhang

摘要

Objective

Although various surgical approaches exist for superior mediastinal lymph node dissection in thyroid cancer, each technique has significant limitations. We present a novel surgical approach via the lateral cervical route that provides an alternative for thyroid cancer patients requiring this procedure.

Methods

We conducted a retrospective analysis on patients who underwent superior mediastinal lymph node dissection (SMLND) via the lateral cervical approach at an academic tertiary care center between June 2023 and December 2024. Surgical safety, efficacy, and short-term outcomes were evaluated.

Results

Our cohort consisted of 21 patients who successfully underwent superior mediastinal lymph node dissection via the lateral cervical approach without severe intraoperative complications. The mean operative time was 153.14 ± 37.52 min, and the average intraoperative blood loss was 54.05 ± 18.84 mL. No in-hospital deaths or uncontrollable intraoperative hemorrhages were observed. The mean postoperative hospital stay was 5.67 ± 0.91 days. Postoperative complications included chylous leakage in 3 cases and hoarseness in 2 cases. All patients achieved macroscopically complete resection; the average number of superior mediastinal lymph nodes dissected was 7.86 ± 3.12. Follow-up at 3–6 months revealed no abnormal elevation of thyroglobulin levels or imaging evidence of recurrent lymphadenopathy.

Conclusion

Our results suggest that this novel lateral cervical approach for SMLND is both safe and effective, offering an alternative option for surgeons managing this condition.

Clinical Trial Information This study was registered on the Clinical Trials Registry (NCT06793579) on January 21, 2025.