Scholarlink

Objective <p>To investigate the value of cardiac magnetic resonance feature tracking (CMR-FT) in evaluating patients with nondilated left-ventricular cardiomyopathy and preserved left-ventricular ejection fraction (NDLVC-pLVEF).</p> Methods <p>This retrospective study included 188 patients with NDLVC and normal left-ventricular ejection fraction (LVEF, ≥ 50%) who underwent cardiac magnetic resonance at Beijing Anzhen Hospital between January 2018 and January 2025, along with 78 age- and sex-matched healthy controls. Using CVI42 postprocessing software, conventional left/right-ventricular function parameters and left-ventricular global strain parameters—including left-ventricular global radial strain (LVGRS), left-ventricular global circumferential strain (LVGCS), and left-ventricular global longitudinal strain (LVGLS)—were obtained. Intergroup differences were analyzed, and the diagnostic performance of strain parameters was evaluated using receiver-operating characteristic (ROC) curve analysis.</p> Results <p>Compared with controls, the NDLVC-pLVEF group exhibited significantly increased absolute values of left-ventricular myocardial mass and LVGLS (<i>P</i> &lt; 0.05), whereas those of LVEF, LVGRS, and LVGCS were significantly decreased (<i>P</i> &lt; 0.05). ROC analysis revealed that the cut-off values of LVGRS, LVGCS, and LVGLS for discriminating the two groups were 36.66%, − 18.49%, and − 13.90%, with sensitivities of 78.70%, 53.20%, and 68.60%; specificities of 64.10%, 74.40%, and 74.40%, and area under the curve values of 0.745, 0.651, and 0.763, respectively.</p> Conclusion <p>CMR-FT demonstrates diagnostic value in identifying patients with NDLVC-pLVEF, with LVGRS, LVGCS, and LVGLS showing considerable diagnostic performance.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Evaluation of nondilated left-ventricular cardiomyopathy with preserved ejection fraction using cardiac magnetic resonance feature tracking

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月25日

查看全文
  • Chunlong Yan,
  • Shuang Li,
  • Baiyan Zhuang,
  • Shujuan Yang,
  • Jiayi Liu,
  • Lei Xu

摘要

Objective

To investigate the value of cardiac magnetic resonance feature tracking (CMR-FT) in evaluating patients with nondilated left-ventricular cardiomyopathy and preserved left-ventricular ejection fraction (NDLVC-pLVEF).

Methods

This retrospective study included 188 patients with NDLVC and normal left-ventricular ejection fraction (LVEF, ≥ 50%) who underwent cardiac magnetic resonance at Beijing Anzhen Hospital between January 2018 and January 2025, along with 78 age- and sex-matched healthy controls. Using CVI42 postprocessing software, conventional left/right-ventricular function parameters and left-ventricular global strain parameters—including left-ventricular global radial strain (LVGRS), left-ventricular global circumferential strain (LVGCS), and left-ventricular global longitudinal strain (LVGLS)—were obtained. Intergroup differences were analyzed, and the diagnostic performance of strain parameters was evaluated using receiver-operating characteristic (ROC) curve analysis.

Results

Compared with controls, the NDLVC-pLVEF group exhibited significantly increased absolute values of left-ventricular myocardial mass and LVGLS (P < 0.05), whereas those of LVEF, LVGRS, and LVGCS were significantly decreased (P < 0.05). ROC analysis revealed that the cut-off values of LVGRS, LVGCS, and LVGLS for discriminating the two groups were 36.66%, − 18.49%, and − 13.90%, with sensitivities of 78.70%, 53.20%, and 68.60%; specificities of 64.10%, 74.40%, and 74.40%, and area under the curve values of 0.745, 0.651, and 0.763, respectively.

Conclusion

CMR-FT demonstrates diagnostic value in identifying patients with NDLVC-pLVEF, with LVGRS, LVGCS, and LVGLS showing considerable diagnostic performance.