Scholarlink

Background <p>The prognosis and quality of life for patients undergoing hemodialysis (HD) are significantly compromised by dysfunctions in arteriovenous grafts (AVG). This study aimed to develop and validate a risk prediction model for factors influencing both short- and long-term primary patency rates in HD patients with AVG.</p> Methods <p>The single-center retrospective study comprised 354 HD patients who had undergone AVG creation. Using Kaplan–Meier survival analysis and Cox regression models, we evaluated the patency rates of AVG and identified associated independent risk factors based on retrospectively collected clinical data.</p> Results <p>The primary&#xa0;patency&#xa0;rates of the patients with AVG&#xa0;at 6&#xa0;months, 1&#xa0;year, and 2&#xa0;years were&#xa0;82.49%, 50%, and 16.95%, respectively. The multivariate Cox regression analysis revealed that the brachial arterial blood flow and draining venous diameter at 1&#xa0;month post-operatively were independent predictors of newly created AVG patency at 6&#xa0;months. Furthermore, at 1&#xa0;month post-operatively, the brachial artery blood flow, draining vein diameter, and history of central venous catheter (HR 0.480 (0.281, 0.820), <i>p</i> = 0.007) were independent risk predictors for failure of newly created AVG at 12&#xa0;months.</p> Conclusion <p>This study revealed that these parameters, including brachial arterial blood flow, draining vein diameter, and history of central venous catheter, could be applied to predict&#xa0;short-&#xa0;and long-term&#xa0;risks&#xa0;for&#xa0;AVG patency&#xa0;loss.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Development of a prediction model to estimate short- and long-term clinical outcomes in arteriovenous grafts for hemodialysis patients

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月30日

查看全文
  • Bin Zhao,
  • Shen Zhan,
  • Lihong Zhang,
  • Hui Wang,
  • Gang Fu,
  • Shanshan Guo,
  • Yuzhu Wang

摘要

Background

The prognosis and quality of life for patients undergoing hemodialysis (HD) are significantly compromised by dysfunctions in arteriovenous grafts (AVG). This study aimed to develop and validate a risk prediction model for factors influencing both short- and long-term primary patency rates in HD patients with AVG.

Methods

The single-center retrospective study comprised 354 HD patients who had undergone AVG creation. Using Kaplan–Meier survival analysis and Cox regression models, we evaluated the patency rates of AVG and identified associated independent risk factors based on retrospectively collected clinical data.

Results

The primary patency rates of the patients with AVG at 6 months, 1 year, and 2 years were 82.49%, 50%, and 16.95%, respectively. The multivariate Cox regression analysis revealed that the brachial arterial blood flow and draining venous diameter at 1 month post-operatively were independent predictors of newly created AVG patency at 6 months. Furthermore, at 1 month post-operatively, the brachial artery blood flow, draining vein diameter, and history of central venous catheter (HR 0.480 (0.281, 0.820), p = 0.007) were independent risk predictors for failure of newly created AVG at 12 months.

Conclusion

This study revealed that these parameters, including brachial arterial blood flow, draining vein diameter, and history of central venous catheter, could be applied to predict short- and long-term risks for AVG patency loss.