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Purpose <p>This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15–45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.</p> Methods <p>A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.</p> Results <p>The mean age of pregnant women was 32&#xa0;years, while non-pregnant women averaged 38&#xa0;years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.</p> Conclusions <p>The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.</p>

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Comparison of the clinical outcomes of COVID-19 in pregnant and non-pregnant patients of reproductive age

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月29日

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  • Nazila Karzad,
  • Simin Taghavi,
  • Ata Mahmoodpoor,
  • Seied Hadi Saghaleini,
  • Saeid Safiri,
  • Pouya Hosseinzadeh

摘要

Purpose

This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15–45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.

Methods

A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.

Results

The mean age of pregnant women was 32 years, while non-pregnant women averaged 38 years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.

Conclusions

The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.