Scholarlink

Background <p>Alcohol use disorder (AUD) is a problematic pattern of drinking that can cause significant impairment or distress. Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel noninvasive technique permitting incision-less ablative treatment, which may be effective for AUD.</p> Case Presentation <p>We present the case of a 54-year-old man diagnosed with AUD for 30 years. After bilateral nucleus accumbens (NAc) MRgFUS, his craving for alcohol decreased markedly from 6 to 0, and he remained abstinent throughout the follow-up (12 months). Moreover, psychiatric and neuropsychological assessments showed improvements in depression, anxiety, sleep, and quality of life. Besides, he did not have any serious adverse effects during the whole follow-up period.</p> Conclusions <p>This case report suggests the feasibility and potential of NAc ablation via MRgFUS in treating severe AUD. Subsequent multi-sample double-blind controlled trials need to be further studied. The effect of MRgFUS on the use disorders of other substances also requires further research.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Treatment of alcohol use disorder via magnetic resonance-guided focused ultrasound ablation surgery

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年1月14日

查看全文
  • Fang Wang,
  • Halimureti Paerhati,
  • Zhengyu Lin,
  • Shuangbao Liu,
  • Bomin Sun,
  • Dianyou Li

摘要

Background

Alcohol use disorder (AUD) is a problematic pattern of drinking that can cause significant impairment or distress. Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel noninvasive technique permitting incision-less ablative treatment, which may be effective for AUD.

Case Presentation

We present the case of a 54-year-old man diagnosed with AUD for 30 years. After bilateral nucleus accumbens (NAc) MRgFUS, his craving for alcohol decreased markedly from 6 to 0, and he remained abstinent throughout the follow-up (12 months). Moreover, psychiatric and neuropsychological assessments showed improvements in depression, anxiety, sleep, and quality of life. Besides, he did not have any serious adverse effects during the whole follow-up period.

Conclusions

This case report suggests the feasibility and potential of NAc ablation via MRgFUS in treating severe AUD. Subsequent multi-sample double-blind controlled trials need to be further studied. The effect of MRgFUS on the use disorders of other substances also requires further research.