<p>To explore the influence of spatial heterogeneity on Zika virus (ZIKV), we formulate a reaction-diffusion model with a saturated incidence rate to better capture these real world dynamics. The basic reproduction number <InlineEquation ID="IEq1"> <EquationSource Format="MATHML"><math> <msub> <mi mathvariant="fraktur">R</mi> <mn>0</mn> </msub> </math></EquationSource> <EquationSource Format="TEX">$\mathfrak{R}_{0}$</EquationSource> </InlineEquation> is derived, and threshold dynamics are established. When <InlineEquation ID="IEq2"> <EquationSource Format="MATHML"><math> <msub> <mi mathvariant="fraktur">R</mi> <mn>0</mn> </msub> <mo>&lt;</mo> <mn>1</mn> </math></EquationSource> <EquationSource Format="TEX">$\mathfrak{R}_{0}&lt;1$</EquationSource> </InlineEquation>, the disease will eventually die out; when <InlineEquation ID="IEq3"> <EquationSource Format="MATHML"><math> <msub> <mi mathvariant="fraktur">R</mi> <mn>0</mn> </msub> <mo>&gt;</mo> <mn>1</mn> </math></EquationSource> <EquationSource Format="TEX">$\mathfrak{R}_{0}&gt;1$</EquationSource> </InlineEquation>, the infection becomes uniformly persistent, and the system admits at least one endemic equilibrium. Numerical simulations validate the theoretical findings and further illustrate how spatial heterogeneity affects the spread and persistence of ZIKV. These findings underscore the importance of region specific control measures in managing ZIKV transmission.</p>

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Dynamics of a Zika epidemic model with saturated incidence in spatially heterogeneous environments

  • Qian Ding,
  • Shuangshuang Zhou,
  • Shubo Chen,
  • Yanfei Dai

摘要

To explore the influence of spatial heterogeneity on Zika virus (ZIKV), we formulate a reaction-diffusion model with a saturated incidence rate to better capture these real world dynamics. The basic reproduction number R 0 $\mathfrak{R}_{0}$ is derived, and threshold dynamics are established. When R 0 < 1 $\mathfrak{R}_{0}<1$ , the disease will eventually die out; when R 0 > 1 $\mathfrak{R}_{0}>1$ , the infection becomes uniformly persistent, and the system admits at least one endemic equilibrium. Numerical simulations validate the theoretical findings and further illustrate how spatial heterogeneity affects the spread and persistence of ZIKV. These findings underscore the importance of region specific control measures in managing ZIKV transmission.