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Background <p>Increasing dental implant use correlates with rising biological complications. For severe peri-implantitis with significant bone loss, choosing the right sustaining treatment is challenging, as nonsurgical methods often fail. This case details a novel management approach for a male patient with serious peri-implantitis, specifically highlighting the initial use of deer antler xenografts in such a procedure.</p> Case presentation <p>A 42-year-old Iranian male presented with significant challenges, including 8&#xa0;mm of vertical bone loss and a probing depth of 12&#xa0;mm around a bone-level Interlock implant (4*11&#xa0;mm). The novel treatment approach incorporated deer antler xenografts, a titanium mesh to maintain space, and a collagen membrane to encourage guided bone regeneration. Follow-up evaluations, both 2D and 3D, four months postsurgery, revealed complete bone regeneration up to the rough neck of the implant. Furthermore, 24&#xa0;months of follow-up after the delivery of the crown showed stable results.</p> Conclusion <p>This case illustrates the promising potential of deer antler-derived xenografts in addressing severe peri-implantitis. It emphasizes the necessity for further clinical trials to validate these observations and enhance treatment protocols.</p>

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First-time use of deer antler-derived xenografts for management of severe peri-implantitis with titanium mesh: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年5月17日

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  • Mahdi Kadkhodazadeh,
  • Aida Kheiri

摘要

Background

Increasing dental implant use correlates with rising biological complications. For severe peri-implantitis with significant bone loss, choosing the right sustaining treatment is challenging, as nonsurgical methods often fail. This case details a novel management approach for a male patient with serious peri-implantitis, specifically highlighting the initial use of deer antler xenografts in such a procedure.

Case presentation

A 42-year-old Iranian male presented with significant challenges, including 8 mm of vertical bone loss and a probing depth of 12 mm around a bone-level Interlock implant (4*11 mm). The novel treatment approach incorporated deer antler xenografts, a titanium mesh to maintain space, and a collagen membrane to encourage guided bone regeneration. Follow-up evaluations, both 2D and 3D, four months postsurgery, revealed complete bone regeneration up to the rough neck of the implant. Furthermore, 24 months of follow-up after the delivery of the crown showed stable results.

Conclusion

This case illustrates the promising potential of deer antler-derived xenografts in addressing severe peri-implantitis. It emphasizes the necessity for further clinical trials to validate these observations and enhance treatment protocols.