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Background <p>Tanycytic ependymoma (TCE) is a rare grade II ependymoma primarily located in the spinal cord, arising from tanycytes. The average age of onset is 34.5&#xa0;years. Definitive diagnosis is achieved through histological analysis. This case report highlights the complete symptomatic resolution following successful surgical intervention in a patient with a rare spinal TCE. It underscores the importance of early diagnosis and treatment, as timely intervention can significantly enhance a patient’s chance for full recovery.</p> Case presentation <p>A 23-year-old Syrian woman with a year of worsening lower back pain and mild paresthesias was diagnosed with a TCE after magnetic resonance imaging (MRI) revealed an intramedullary mass at T10-T11. Surgical resection was successfully performed with care to minimize bleeding. Histological analysis confirmed the tumor type through spindle cell morphology and GFAP positivity. The patient achieved full recovery 6 months post-surgery.</p> Conclusion <p>Due to nonspecific radiological features of TCE, timely diagnosis requires thorough neurological evaluation, and early referral to specialized centers is advised for suspected cases, as prompt surgical resection can enhance outcomes.</p>

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Complete symptomatic resolution following surgical resection of a spinal tanycytic ependymoma: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月22日

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  • Saja Karaja,
  • Khayry Al-Shami,
  • William Borghol,
  • Mulham Alkassem,
  • Habib Jarbouh,
  • Wardan Almir Tamer

摘要

Background

Tanycytic ependymoma (TCE) is a rare grade II ependymoma primarily located in the spinal cord, arising from tanycytes. The average age of onset is 34.5 years. Definitive diagnosis is achieved through histological analysis. This case report highlights the complete symptomatic resolution following successful surgical intervention in a patient with a rare spinal TCE. It underscores the importance of early diagnosis and treatment, as timely intervention can significantly enhance a patient’s chance for full recovery.

Case presentation

A 23-year-old Syrian woman with a year of worsening lower back pain and mild paresthesias was diagnosed with a TCE after magnetic resonance imaging (MRI) revealed an intramedullary mass at T10-T11. Surgical resection was successfully performed with care to minimize bleeding. Histological analysis confirmed the tumor type through spindle cell morphology and GFAP positivity. The patient achieved full recovery 6 months post-surgery.

Conclusion

Due to nonspecific radiological features of TCE, timely diagnosis requires thorough neurological evaluation, and early referral to specialized centers is advised for suspected cases, as prompt surgical resection can enhance outcomes.