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Background <p>Left atrial myxomas are rare, potentially life-threatening benign cardiac tumors. Early surgical excision is recommended to prevent embolic events, obstruction, and sudden death.</p> Case summary <p>A 72-year-old Turkish woman presented with exertional dyspnea and palpitations. Transthoracic echocardiography demonstrated a 4.7&#xa0;cm × 2.7&#xa0;cm mobile left atrial mass attached to the interatrial septum and prolapsing into the mitral orifice with a mean transmitral gradient of 9&#xa0;mmHg and no evidence of embolization. Elective median sternotomy under cardiopulmonary bypass via a right atriotomy–transseptal approach enabled en bloc excision with primary septal closure. Postoperative transesophageal echocardiography confirmed complete resection with preserved mitral valve function, and the mean transmitral gradient fell immediately to ~1.3–1.4&#xa0;mmHg, indicating prompt hemodynamic normalization. Recovery was uneventful, and the patient was discharged on postoperative day 8.</p> Discussion <p>This case demonstrates the rapid reversal of myxoma-related functional mitral stenosis following valve-sparing transseptal excision, with immediate normalization of the mean transmitral gradient.</p>

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Large left atrial myxoma with functional mitral stenosis: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月26日

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  • Burak Bozkurt,
  • Bingül Dilekçi Şahin,
  • Üzeyir Yılmaz,
  • Güler Gülsen Ersoy

摘要

Background

Left atrial myxomas are rare, potentially life-threatening benign cardiac tumors. Early surgical excision is recommended to prevent embolic events, obstruction, and sudden death.

Case summary

A 72-year-old Turkish woman presented with exertional dyspnea and palpitations. Transthoracic echocardiography demonstrated a 4.7 cm × 2.7 cm mobile left atrial mass attached to the interatrial septum and prolapsing into the mitral orifice with a mean transmitral gradient of 9 mmHg and no evidence of embolization. Elective median sternotomy under cardiopulmonary bypass via a right atriotomy–transseptal approach enabled en bloc excision with primary septal closure. Postoperative transesophageal echocardiography confirmed complete resection with preserved mitral valve function, and the mean transmitral gradient fell immediately to ~1.3–1.4 mmHg, indicating prompt hemodynamic normalization. Recovery was uneventful, and the patient was discharged on postoperative day 8.

Discussion

This case demonstrates the rapid reversal of myxoma-related functional mitral stenosis following valve-sparing transseptal excision, with immediate normalization of the mean transmitral gradient.