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Background <p>Fibrosarcoma is a rare, invasive soft tissue sarcoma that is more common in males aged 30–60&#xa0;years. It accounts for 1% of all malignancies in the human body. Treatment is radical surgical removal, radiotherapy, and chemotherapy.</p> Case presentation <p>A 58-year-old Khorasani Persian male patient with a complaint of expansion, pain, and paresthesia in the left maxillary quadrant was diagnosed with infiltrative high-grade sarcoma. Tumoral cells were strongly diffuse positive for vimentin and negative for S100 and desmin, indicating high-grade adult fibrosarcoma.</p> Conclusion <p>This report presents a rare case of a fibrosarcoma causing paresthesia, pain, and expansion in the maxilla with maxillary sinus invasion, which requires early diagnosis and immediate referral.</p>

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Fibrosarcoma of the maxilla with maxillary sinus invasion: a case report and review of the literature

  • 期刊论文

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  • 发表日期：

    2025年5月28日

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  • Nazanin Mahdavi,
  • Samira Derakhshan,
  • Mahsa Etemadi

摘要

Background

Fibrosarcoma is a rare, invasive soft tissue sarcoma that is more common in males aged 30–60 years. It accounts for 1% of all malignancies in the human body. Treatment is radical surgical removal, radiotherapy, and chemotherapy.

Case presentation

A 58-year-old Khorasani Persian male patient with a complaint of expansion, pain, and paresthesia in the left maxillary quadrant was diagnosed with infiltrative high-grade sarcoma. Tumoral cells were strongly diffuse positive for vimentin and negative for S100 and desmin, indicating high-grade adult fibrosarcoma.

Conclusion

This report presents a rare case of a fibrosarcoma causing paresthesia, pain, and expansion in the maxilla with maxillary sinus invasion, which requires early diagnosis and immediate referral.