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Introduction <p>The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension.</p> Case presentation <p>A 35-year-old African male patient referred to our institution, presenting with severe hypertension for 4&#xa0;years. Renal magnetic resonance imaging showed a solid 9-mm lesion in the right upper pole cortex with high signal intensity on diffusion-weighted imaging, isointense on T2, and enhanced after contrast injection. The patient underwent an open right partial nephrectomy. The diagnosis of reninomas was confirmed by histopathological examination.</p> Conclusion <p>Nephron-sparing surgery should be considered in patients with juxtaglomerular tumors. This technique allows prompt recovery with the preservation of significant renal function.</p>

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Juxtaglomerular cell tumor: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月29日

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  • Kays Chaker,
  • Syrine Tlili,
  • Alia Zehani,
  • Nader Gharbia,
  • Mariem Snoussi,
  • Wassim Frikha,
  • Hiba Ghabi,
  • Boutheina Mosbahi,
  • Ikram Mami,
  • Mohamed Karim Zouaghi,
  • Yassine Nouira

摘要

Introduction

The tumor produces an excessive amount of renin resulting in secondary hyperaldosteronism, thereby causing hypertension with hypokalemia. The authors describe a case of reninoma in a young man, who presented with malignant hypertension.

Case presentation

A 35-year-old African male patient referred to our institution, presenting with severe hypertension for 4 years. Renal magnetic resonance imaging showed a solid 9-mm lesion in the right upper pole cortex with high signal intensity on diffusion-weighted imaging, isointense on T2, and enhanced after contrast injection. The patient underwent an open right partial nephrectomy. The diagnosis of reninomas was confirmed by histopathological examination.

Conclusion

Nephron-sparing surgery should be considered in patients with juxtaglomerular tumors. This technique allows prompt recovery with the preservation of significant renal function.