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Background <p>Cardiac myxoma with glandular differentiation is a rare finding. It accounts for approximately ≤ 3% of all cardiac myxomas. The presence of cellular atypia resembling adenocarcinoma is an extremely rare finding in cardiac myxoma.</p> Case presentation <p>Here, we present a case of villiform cardiac myxoma with atypical glandular differentiation in a 16-year-old Indo-Aryan girl, which was initially mistaken as metastatic adenocarcinoma on routine histology.</p> Conclusion <p>A thorough histopathological examination, supported by immunohistochemical and radiological correlation, assists in accurate diagnosis and concurrently evades the misdiagnosis of metastatic adenocarcinoma.</p>

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Villiform cardiac myxoma with atypical glandular differentiation in a young girl: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年4月23日

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  • Sangram Keshari Behera,
  • Debahuti Mohapatra,
  • Debirupa De,
  • Krishna Sai Sharan,
  • Swagatika Samal

摘要

Background

Cardiac myxoma with glandular differentiation is a rare finding. It accounts for approximately ≤ 3% of all cardiac myxomas. The presence of cellular atypia resembling adenocarcinoma is an extremely rare finding in cardiac myxoma.

Case presentation

Here, we present a case of villiform cardiac myxoma with atypical glandular differentiation in a 16-year-old Indo-Aryan girl, which was initially mistaken as metastatic adenocarcinoma on routine histology.

Conclusion

A thorough histopathological examination, supported by immunohistochemical and radiological correlation, assists in accurate diagnosis and concurrently evades the misdiagnosis of metastatic adenocarcinoma.