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Background <p>Cervical esophageal adenocarcinoma is a rare tumor often associated with Barrett’s esophagus, and its prevalence is lower than distal esophageal adenocarcinoma. Upper esophageal malignancies are usually squamous cell carcinomata; about 5% of these cases are seen during upper gastrointestinal endoscopy.</p> Case presentation <p>We present a patient (a 39-year-old Iranian man) with invasive adenocarcinoma of the proximal third of the esophagus, who was referred to the hospital with no endoscopic or histopathologic evidence of Barrett’s esophagus. We discuss the probable cause of this tumor and treatment options and emphasize the importance of recognizing and managing this rare disease.</p> Conclusions <p>This case highlights the rarity of this adenocarcinoma and emphasizes the potential of chemotherapy as a standalone treatment, as well as the need for personalized therapeutic strategies and further research for the management of esophageal cancer.</p>

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Management of a patient with primary adenocarcinoma of the proximal third of the esophagus: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月19日

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  • Ali Saeidpour parizi,
  • Ahmad Enhesari,
  • Vahid Moazed,
  • Sara Shafieipour,
  • Samira Shahba,
  • Alaa Hamza Hermis,
  • Mohammad Ali Zakeri

摘要

Background

Cervical esophageal adenocarcinoma is a rare tumor often associated with Barrett’s esophagus, and its prevalence is lower than distal esophageal adenocarcinoma. Upper esophageal malignancies are usually squamous cell carcinomata; about 5% of these cases are seen during upper gastrointestinal endoscopy.

Case presentation

We present a patient (a 39-year-old Iranian man) with invasive adenocarcinoma of the proximal third of the esophagus, who was referred to the hospital with no endoscopic or histopathologic evidence of Barrett’s esophagus. We discuss the probable cause of this tumor and treatment options and emphasize the importance of recognizing and managing this rare disease.

Conclusions

This case highlights the rarity of this adenocarcinoma and emphasizes the potential of chemotherapy as a standalone treatment, as well as the need for personalized therapeutic strategies and further research for the management of esophageal cancer.