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Objective <p>This study aimed to determine the seasonal variations in frequency and outcomes of HBSS-related morbidities admitted over two years into a tertiary hospital emergency ward in Lagos, Nigeria. A retrospective descriptive study was conducted using hospital records of HBSS patients admitted into the emergency ward from January 2021 to December 2022. Data on demographics, clinical diagnosis, season of admission, and outcomes were extracted and analyzed using Epi Info version 7. Associations were tested using Chi-square at a significance level of <i>p</i> &lt; 0.05.</p> Results <p>A total of 132 HBSS admissions were recorded (63 in 2021 and 69 in 2022), with a male predominance (54.5%), while the majority aged between 20 and 29 years (55.3%). Vaso-occlusive crisis (VOC) was the most common morbidity (80.6%). Seasonal variations in admissions occurred, which peaked during rainy season months (May, June). The percentage of in-hospital mortality was 5.3% and mortality was seen to be significantly higher among stroke cases (50.0%) than other HBSS morbidities (<i>p</i> = 0.046). Seasonal patterns influenced HBSS morbidity, with VOCs predominating especially during the rainy season.</p>

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Seasonal variations in frequency of acute sickle cell morbidities admitted into an emergency ward in Lagos

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年4月20日

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  • Oziegbe Oghide,
  • Damilola Akinlawon,
  • Akeem Opeyemi Akinbode,
  • Olumide Thomas Adeleke,
  • Enefo Emoruwa,
  • Kristin Emeh Oluwadara Mfon,
  • Chimdalu Okezie Emekekwue,
  • Goodness Ofure Aghulor,
  • Muyiwa Abimbola Ogunyanwo,
  • Love Ehinmwnma Imoukhuede,
  • Esther EnoMonioluwa Efon,
  • Iorhen Akase

摘要

Objective

This study aimed to determine the seasonal variations in frequency and outcomes of HBSS-related morbidities admitted over two years into a tertiary hospital emergency ward in Lagos, Nigeria. A retrospective descriptive study was conducted using hospital records of HBSS patients admitted into the emergency ward from January 2021 to December 2022. Data on demographics, clinical diagnosis, season of admission, and outcomes were extracted and analyzed using Epi Info version 7. Associations were tested using Chi-square at a significance level of p < 0.05.

Results

A total of 132 HBSS admissions were recorded (63 in 2021 and 69 in 2022), with a male predominance (54.5%), while the majority aged between 20 and 29 years (55.3%). Vaso-occlusive crisis (VOC) was the most common morbidity (80.6%). Seasonal variations in admissions occurred, which peaked during rainy season months (May, June). The percentage of in-hospital mortality was 5.3% and mortality was seen to be significantly higher among stroke cases (50.0%) than other HBSS morbidities (p = 0.046). Seasonal patterns influenced HBSS morbidity, with VOCs predominating especially during the rainy season.