Objective <p>This study aimed to investigate the effects of catecholamine administration on ICU patients with acute gastrointestinal injury undergoing invasive mechanical ventilation (IMV).</p> Results <p>During the study period, 425 patients with a median age of 60 years (interquartile range, 48–70), including 290 males (68%), received IMV during their ICU stay. AGI occurred in 287 patients, with an incidence rate of 67.5%. The most common symptom of AGI was gastric retention (50.52%). Multivariate regression analysis results showed the following as risk factors for AGI: the administration of catecholamine drugs (OR: 2.881, 95% CI 1.525 to 5.441, <i>P</i> = 0.001), Acute Physiology and Chronic Health Evaluation II score (OR: 1.119, 95% CI 1.055 to 1.186, <i>P</i> &lt; 0.001), Nutritional Risk Screening 2002 score (OR: 1.416, 95% CI 1.154 to 1.737, <i>P</i> = 0.001), duration of IMV (OR: 1.142, 95% CI 1.108 to 1.207, <i>P</i> &lt; 0.001), and primary disease involving the respiratory system (OR: 2.097, 95% CI 1.179 to 3.731, <i>P</i> = 0.012).</p>

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Exploring the incidence and influencing factors of acute gastrointestinal injury in ICU patients undergoing mechanical ventilation: a retrospective cohort study

  • Mingwei Zhong,
  • Jianhuang Zheng,
  • Ruwei Huang,
  • Zhizhao Jiang,
  • Yizhe Zhong

摘要

Objective

This study aimed to investigate the effects of catecholamine administration on ICU patients with acute gastrointestinal injury undergoing invasive mechanical ventilation (IMV).

Results

During the study period, 425 patients with a median age of 60 years (interquartile range, 48–70), including 290 males (68%), received IMV during their ICU stay. AGI occurred in 287 patients, with an incidence rate of 67.5%. The most common symptom of AGI was gastric retention (50.52%). Multivariate regression analysis results showed the following as risk factors for AGI: the administration of catecholamine drugs (OR: 2.881, 95% CI 1.525 to 5.441, P = 0.001), Acute Physiology and Chronic Health Evaluation II score (OR: 1.119, 95% CI 1.055 to 1.186, P < 0.001), Nutritional Risk Screening 2002 score (OR: 1.416, 95% CI 1.154 to 1.737, P = 0.001), duration of IMV (OR: 1.142, 95% CI 1.108 to 1.207, P < 0.001), and primary disease involving the respiratory system (OR: 2.097, 95% CI 1.179 to 3.731, P = 0.012).